SCHEMBL13337948

SCHEMBL13337948

Cc1ccc(N(c2ccc(C)cc2)c2ccc(C=C(c3ccc(OCC4CO4)cc3)c3ccc(OCC4CO4)cc3)cc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.43
RAB9A P51151 4/20 0.43
NPC1 O15118 3/20 0.43
LMNA P02545 2/20 0.43
MAPT P10636 4/20 0.42
ALDH1A1 P00352 4/20 0.42
HPGD P15428 3/20 0.42
TP53 P04637 2/20 0.42
TSHR P16473 2/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
CYP1A2 P05177 1/20 0.42
PPARG P37231 1/20 0.42
HIF1A Q16665 1/20 0.42
PDK1 Q15118 1/20 0.41
TDP1 Q9NUW8 1/20 0.40
KDM4E B2RXH2 1/20 0.40
CYP2D6 P10635 1/20 0.39
PKM P14618 2/20 0.39
GAA P10253 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23309751 0.85 APP (0.50) SMN1; SMN2RAB9ANPC1LMNAMAPT
SCHEMBL23309790 0.82 APP (0.47) SMN1; SMN2RAB9ANPC1LMNAMAPT
SCHEMBL279561 0.82 PTGS2 (0.41) SMN1; SMN2MAPTALDH1A1HPGDTP53
SCHEMBL9607511 0.81 ALDH1A1 (0.51) SMN1; SMN2RAB9ANPC1LMNAMAPT
SCHEMBL13923790 0.80 CYP2D6 (0.50) RAB9ANPC1LMNAMAPTALDH1A1
SCHEMBL28490346 0.80 TDP1 (0.61) SMN1; SMN2LMNAMAPTALDH1A1HPGD
SCHEMBL14174021 0.79 CYP2D6 (0.49) NPC1LMNAMAPTALDH1A1HPGD
SCHEMBL5008020 0.79 CYP2D6 (0.49) NPC1LMNAMAPTALDH1A1HPGD
SCHEMBL12269357 0.79 CYP2D6 (0.49) NPC1LMNAMAPTALDH1A1HPGD
SCHEMBL10083672 0.79 ALDH1A1 (0.42) SMN1; SMN2RAB9ANPC1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7718333-B2 Electrophotographic photoconductor and method of preparing same RICOH COMPANY, LTD. (JP) 2010-05-18 US disclosed
US-20080063959-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR AND METHOD OF PREPARING SAME NAGAI KAZUKIYO 2008-03-13 US disclosed
US-7279260-B2 Electrophotographic photoconductor having a crosslinked resin layer and method of preparing an electrophotographic photoconductor RICOH COMPANY, LTD. (JP) 2007-10-09 US disclosed
US-7279260-B2 Electrophotographic photoconductor having a crosslinked resin layer and method of preparing an electrophotographic photoconductor RICOH COMPANY, LTD. (JP) 2007-10-09 US disclosed