Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 7/20 | 0.34 |
| ▸ | MEN1 | O00255 | 6/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.34 |
| ▸ | POLB | P06746 | 5/20 | 0.34 |
| ▸ | ATM | Q13315 | 2/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2832354 | 0.95 | SIRT2 (0.37) | SIRT2TDP1NPSR1MEN1KMT2A | |
| SCHEMBL13287535 | 0.93 | SIRT2 (0.36) | SIRT2TDP1NPSR1MEN1KMT2A | |
| SCHEMBL16580122 | 0.90 | FOLH1 (0.38) | SIRT2MEN1KMT2AFOLH1 | |
| SCHEMBL2495998 | 0.87 | FOLH1 (0.38) | SIRT2TDP1NPSR1MEN1KMT2A | |
| SCHEMBL17997540 | 0.87 | FOLH1 (0.33) | SIRT2TDP1NPSR1MEN1KMT2A | |
| SCHEMBL14674925 | 0.86 | FOLH1 (0.34) | SIRT2TDP1MEN1KMT2APOLB | |
| SCHEMBL15501039 | 0.86 | FPR2 (0.32) | TDP1MEN1KMT2AATMFOLH1 | |
| SCHEMBL9982656 | 0.86 | FOLH1 (0.47) | FOLH1 | |
| SCHEMBL1742288 | 0.85 | TDP1 (0.34) | TDP1NPSR1MEN1KMT2APOLB | |
| SCHEMBL2830839 | 0.84 | FOLH1 (0.41) | SIRT2TDP1NPSR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010065899-A2 | TECHNETIUM-AND RHENIUM-BIS(HETEROARYL)COMPLEXES AND METHODS OF USE THEREOF | MOLECULAR INSIGHT PHARMACEUTICALS, INC. (US) | 2010-06-10 | — | — | WO | disclosed |