Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 5/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2831636 | 0.97 | FOLH1 (0.35) | FPR2TDP1FOLH1 | |
| SCHEMBL17690558 | 0.97 | FOLH1 (0.35) | FPR2TDP1FOLH1 | |
| SCHEMBL13237046 | 0.95 | FOLH1 (0.36) | FOLH1 | |
| SCHEMBL13287694 | 0.93 | CTSK (0.31) | — | |
| SCHEMBL17685197 | 0.93 | FOLH1 (0.30) | FOLH1 | |
| SCHEMBL17685198 | 0.92 | — | — | |
| SCHEMBL2832354 | 0.92 | SIRT2 (0.37) | TDP1FOLH1ATMMEN1KMT2A | |
| SCHEMBL11936778 | 0.91 | — | — | |
| SCHEMBL2835915 | 0.89 | FOLH1 (0.36) | FPR2TDP1FOLH1MEN1KMT2A | |
| SCHEMBL1742288 | 0.89 | TDP1 (0.34) | TDP1FOLH1ATMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2706057-A1 | Bis(imidazolyl)compounds and radionuclide complexes | Molecular Insight Pharmaceuticals, Inc. (US) | 2014-03-12 | — | — | EP | disclosed |