Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | CPT2 | P23786 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | HMGCR | P04035 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL665258 | 0.83 | TSHR (0.45) | TSHRALDH1A1TP53KDM4EFFAR1 | |
| SCHEMBL8077843 | 0.78 | TSHR (0.33) | TSHRALDH1A1TP53 | |
| SCHEMBL2056465 | 0.78 | TSHR (0.33) | TSHRALDH1A1TP53 | |
| SCHEMBL1409381 | 0.78 | — | — | |
| SCHEMBL212208 | 0.77 | — | — | |
| SCHEMBL6984438 | 0.77 | TDP1 (0.43) | ALDH1A1KDM4EFFAR1CPT2TDP1 | |
| SCHEMBL23158507 | 0.77 | TSHR (0.32) | TSHRALDH1A1TP53FFAR1CPT2 | |
| SCHEMBL11324877 | 0.76 | — | — | |
| SCHEMBL433760 | 0.76 | KDM4E (0.54) | TSHRALDH1A1KDM4EFFAR1CPT2 | |
| SCHEMBL13251256 | 0.76 | ALDH1A1 (0.33) | TSHRALDH1A1KDM4EFFAR1CPT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023002338-A1 | COMPOSITIONS, METHODS OF MAKING AND USING SAME FOR THE DELIVERY OF ULCEROGENIC DRUGS THEREOF | AVACA PHARMA PRIVATE LIMITED (IN) | 2023-01-26 | — | — | WO | disclosed |
| US-7728153-B2 | Method for the asymmetric synthesis of beta-lactone compounds | THE BURNHAM INSTITUTE FOR MEDICAL RESEARCH (US) | 2010-06-01 | — | — | US | disclosed |