SCHEMBL433760

SCHEMBL433760

CC(C)(C)CC(C)(C)CC(=O)O

nearest known ligand 0.68

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.54
FFAR1 O14842 1/20 0.54
CPT2 P23786 1/20 0.54
TDP1 Q9NUW8 1/20 0.54
HMGCR P04035 1/20 0.50
CHRM1 P11229 1/20 0.50
TBXA2R P21731 1/20 0.50
ADRA1A P35348 1/20 0.50
CYP2C19 P33261 2/20 0.48
HIF1A Q16665 2/20 0.48
TSHR P16473 2/20 0.48
CYP2D6 P10635 1/20 0.48
ALDH1A1 P00352 2/20 0.38
BHMT Q93088 3/20 0.36
FFAR3 O14843 1/20 0.33
POLB P06746 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methane SCHEMBL371521 0.97 KDM4E (0.52) KDM4EFFAR1CPT2TDP1HMGCR
SCHEMBL1979018 0.97 KDM4E (0.52) KDM4EFFAR1CPT2TDP1HMGCR
SCHEMBL17187568 0.97 KDM4E (0.52) KDM4EFFAR1CPT2TDP1HMGCR
SCHEMBL557257 0.88 KDM4E (0.59) KDM4EFFAR1CPT2TDP1HMGCR
SCHEMBL12808778 0.86 KDM4E (0.56) KDM4EFFAR1CPT2TDP1HMGCR
SCHEMBL16675248 0.85 KDM4E (0.46) KDM4EFFAR1CPT2TDP1HMGCR
SCHEMBL48109 0.82 KDM4E (0.65) KDM4EFFAR1CPT2TDP1HMGCR
SCHEMBL30854909 0.82 KDM4E (0.65) KDM4EFFAR1CPT2TDP1HMGCR
SCHEMBL19068470 0.80 KDM4E (0.38) KDM4EFFAR1CPT2TDP1HMGCR
SCHEMBL11439787 0.79 KDM4E (0.62) KDM4EFFAR1CPT2TDP1HMGCR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4399241-A1 TYRE FOR VEHICLE WHEELS Pirelli Tyre S.p.A. (IT) 2024-07-17 EP claimed
WO-2023037239-A1 TYRE FOR VEHICLE WHEELS PIRELLI TYRE S.P.A. (IT) 2023-03-16 WO claimed
US-12577371-B2 Oxidatively curable coating composition MILLIKEN INDUSTRIALS LIMITED (GB) 2026-03-17 US disclosed
US-12570851-B2 Liquids MILLIKEN INDUSTRIALS LIMITED (GB) 2026-03-10 US disclosed
EP-3426740-B1 METHOD OF PREPARING AN OXIDATIVELY CURABLE COATING FORMULATION MILLIKEN INDUSTRIALS LTD (GB) 2024-09-11 EP disclosed
US-12077652-B2 Oxidatively curable coating composition MILLIKEN INDUSTRIALS LIMITED (GB) 2024-09-03 US disclosed
EP-3818115-B1 OXIDATIVELY CURABLE COATING COMPOSITION MILLIKEN INDUSTRIALS LTD (GB) 2023-11-22 EP disclosed
US-20230203353-A1 ADHESIVE FOR ENDOSCOPE AND CURED PRODUCT THEREOF, AND ENDOSCOPE AND METHOD FOR PRODUCING THE SAME FUJIFILM CORPORATION (JP) 2023-06-29 US disclosed
US-20230174570-A1 NOVEL TRITERPENE DERIVATIVES AS HIV INHIBITORS HETERO LABS LIMITED (IN) 2023-06-08 US disclosed
EP-3390486-B1 OXIDATIVELY CURABLE COATING COMPOSITION MILLIKEN INDUSTRIALS LTD (GB) 2023-05-03 EP disclosed
CN-112313298-B Oxidatively curable coating compositions 卡特克塞尔科技有限公司 2022-12-02 CN disclosed
US-8211932-B2 Organic compounds and their uses NOVARTIS AG (CH) 2012-07-03 US disclosed
WO-2012010844-A1 PRODUCTION PROCESS FOR POLYOL FOR USE IN LOW BALL REBOUND POLYURETHANE FOAMS NOAKES CHRISTOPHER WICKHAM (CH) 2012-01-26 WO disclosed
US-20110021624-A1 Alpha-Amino-N-Substituted Amides, Pharmaceutical Composition Containing Them and Uses Thereof SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) 2011-01-27 US disclosed
US-20110015196-A1 LUPEOL-TYPE TRITERPENE DERIVATIVES AS ANTIVIRALS HETERO RESEARCH FOUNDATION (IN) 2011-01-20 US disclosed
US-20100331243-A1 ORGANIC COMPOUNDS AND THEIR USES NOVARTIS AG (CH) 2010-12-30 US disclosed
US-7825152-B2 serine protease inhibitors, for the treatment of hepatitis c virus infections NOVARTIS AG (CH) 2010-11-02 US disclosed
US-20100204159-A1 ORGANIC COMPOUNDS AND THEIR USES NOVARTIS AG (CH) 2010-08-12 US disclosed
US-20080132506-A1 Anti-inflammatory medicaments FLYNN DANIEL L 2008-06-05 US disclosed
US-20070286842-A1 Organic Compounds and Their Uses NOVARTIS AG (CH) 2007-12-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100331243-A1 ORGANIC COMPOUNDS AND THEIR USES OAT, OTC, AOX1 KDM4E 4021/4885FFAR1 3129/4885CPT2 51/4885
US-12577371-B2 Oxidatively curable coating composition TET1, JMJD6, SETDB1 KDM4E 56/4885FFAR1 687/4885CPT2 736/4885
US-12570851-B2 Liquids SOD1, GPX4, SMARCC1 KDM4E 1517/4885FFAR1 1346/4885CPT2 2225/4885
US-20110015196-A1 LUPEOL-TYPE TRITERPENE DERIVATIVES AS ANTIVIRALS MAVS, IRF3, LSS KDM4E 3378/4885FFAR1 2631/4885CPT2 1551/4885
US-20110021624-A1 Alpha-Amino-N-Substituted Amides, Pharmaceutical Composition Containing Them and Uses Thereof AADAT, ASNS, AANAT KDM4E 1098/4885FFAR1 1780/4885CPT2 3386/4885
US-20070286842-A1 Organic Compounds and Their Uses OAT, OTC, AOX1 KDM4E 4021/4885FFAR1 3129/4885CPT2 51/4885
US-20230174570-A1 NOVEL TRITERPENE DERIVATIVES AS HIV INHIBITORS CYP51A1, CCR5, CYP4A11 KDM4E 1590/4885FFAR1 2978/4885CPT2 3891/4885
US-20100204159-A1 ORGANIC COMPOUNDS AND THEIR USES OAT, OTC, AOX1 KDM4E 4021/4885FFAR1 3129/4885CPT2 51/4885
US-20080132506-A1 Anti-inflammatory medicaments MIF, PTGES2, TNF KDM4E 3081/4885FFAR1 2547/4885CPT2 2596/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.