SCHEMBL13344155

SCHEMBL13344155

C#Cc1ccc(C)c2ccc(Br)cc12

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PYCR1 P32322 1/20 0.35
CYP1A2 P05177 1/20 0.33
LMNA P02545 1/20 0.32
HPGD P15428 1/20 0.32
TNF P01375 1/20 0.31
ESR2 Q92731 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2022697 0.78 PYCR1 (0.43) PYCR1
SCHEMBL2203417 0.74 CYP1A2 (0.59) CYP1A2HPGD
SCHEMBL29661807 0.69 HSP90AA1 (0.46) PYCR1LMNAHPGD
SCHEMBL4746042 0.69 HSP90AA1 (0.46) PYCR1LMNAHPGD
SCHEMBL3973920 0.67 JAK2 (0.33) PYCR1
SCHEMBL29137849 0.66 PTPN1 (0.39)
SCHEMBL3433348 0.66 PYCR1 (0.42) PYCR1LMNAHPGD
SCHEMBL29658059 0.66 PYCR1 (0.42) PYCR1LMNAHPGD
SCHEMBL20651374 0.66 ALK (0.46) CYP1A2LMNA
SCHEMBL27977187 0.66 SLC22A12 (0.45) CYP1A2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010071227-A1 ALUMINIUM COMPLEXES AND USE THEREOF AS A CATALYST IN INTRAMOLECULAR RING CLOSURE REACTIONS TAKASAGO INTERNATIONAL CORPORATION (JP) 2010-06-24 WO disclosed