Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYCR1 | P32322 | 1/20 | 0.42 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 2/20 | 0.37 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29658059 | 1.00 | PYCR1 (0.42) | PYCR1DGAT1KDM1AKDM1BCYP11B1 | |
| SCHEMBL5958536 | 0.82 | PYCR1 (0.39) | PYCR1DGAT1KDM1AKDM1BNPC1 | |
| SCHEMBL27214759 | 0.81 | ACACB (0.46) | PYCR1DGAT1KDM1AKDM1BCYP11B1 | |
| SCHEMBL56634 | 0.77 | TRPV4 (0.57) | CYP11B1CYP11B2TRPV4 | |
| SCHEMBL2366749 | 0.77 | DGAT1 (0.44) | PYCR1DGAT1KDM1AKDM1BCYP11B1 | |
| SCHEMBL14661873 | 0.77 | DGAT1 (0.39) | PYCR1DGAT1KDM1AKDM1BCYP11B1 | |
| SCHEMBL29661807 | 0.76 | HSP90AA1 (0.46) | PYCR1LMNASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL30111761 | 0.76 | ALDH1A1 (0.42) | CYP11B1CYP11B2TRPV4ALDH1A1CYP2A6 | |
| SCHEMBL434666 | 0.76 | ALDH1A1 (0.42) | CYP11B1CYP11B2TRPV4ALDH1A1CYP2A6 | |
| SCHEMBL4746042 | 0.76 | HSP90AA1 (0.46) | PYCR1LMNASMN1; SMN2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1551834-B1 | SUBSTITUTED QUINAZOLINONE COMPOUNDS | NOVARTIS VACCINES & DIAGNOSTIC (US) | 2010-08-25 | — | — | EP | claimed |
| EP-1502292-A4 | POLYMERIC ANTIREFLECTIVE COATINGS DEPOSITED BY PLASMA ENHANCED CHEMICAL VAPOR DEPOSITION | BREWER SCIENCE INC (US) | 2009-01-21 | — | — | EP | claimed |
| JP-2005524240-A | — | — | 2005-08-11 | — | — | JP | claimed |
| US-6852474-B2 | Polymeric antireflective coatings deposited by plasma enhanced chemical vapor deposition | BREWER SCIENCE INC. (US) | 2005-02-08 | — | — | US | claimed |
| EP-1502292-A1 | POLYMERIC ANTIREFLECTIVE COATINGS DEPOSITED BY PLASMA ENHANCED CHEMICAL VAPOR DEPOSITION | Brewer Science, Inc. (US) | 2005-02-02 | — | — | EP | claimed |
| US-20030224586-A1 | Polymeric antireflective coatings deposited by plasma enhanced chemical vapor deposition | BREWER SCIENCE, INC. | 2003-12-04 | — | — | US | claimed |
| WO-2003094213-A1 | POLYMERIC ANTIREFLECTIVE COATINGS DEPOSITED BY PLASMA ENHANCED CHEMICAL VAPOR DEPOSITION | BREWER SCIENCE, INC. (US) | 2003-11-13 | — | — | WO | claimed |
| US-20240158390-A1 | OTHER HETEROAROMATIC COMPOUNDS HAVING ACTIVITY AGAINST RSV | JANSSEN SCIENCES IRELAND UNLMITED COMPANY (IE) | 2024-05-16 | — | — | US | disclosed |
| EP-3784667-B1 | HETEROAROMATIC COMPOUNDS HAVING ACTIVITY AGAINST RSV | JANSSEN SCIENCES IRELAND UNLIMITED CO (IE) | 2023-08-16 | — | — | EP | disclosed |
| US-11708369-B2 | Heteroaromatic compounds having activity against RSV | Janssen Sciences Ireland Unlimited Company (IE) | 2023-07-25 | — | — | US | disclosed |
| US-11708369-B2 | Heteroaromatic compounds having activity against RSV | Janssen Sciences Ireland Unlimited Company (IE) | 2023-07-25 | — | — | US | disclosed |
| EP-3972964-A1 | OTHER HETEROAROMATIC COMPOUNDS HAVING ACTIVITY AGAINST RSV | Janssen Sciences Ireland Unlimited Company (IE) | 2022-03-30 | — | — | EP | disclosed |
| CN-113874380-A | Other heteroaromatic compounds with anti-RSV activity | 爱尔兰詹森科学公司 | 2021-12-31 | — | — | CN | disclosed |
| EP-1502292-A4 | POLYMERIC ANTIREFLECTIVE COATINGS DEPOSITED BY PLASMA ENHANCED CHEMICAL VAPOR DEPOSITION | BREWER SCIENCE INC (US) | 2009-01-21 | — | — | EP | disclosed |
| US-20070134733-A1 | Raman signature probes and their use in the detection and imaging of molecular processes and structures | PARALLAX BIOSYSTEMS, INC. | 2007-06-14 | — | — | US | disclosed |
| US-20070134733-A1 | Raman signature probes and their use in the detection and imaging of molecular processes and structures | PARALLAX BIOSYSTEMS, INC. | 2007-06-14 | — | — | US | disclosed |
| US-6852474-B2 | Polymeric antireflective coatings deposited by plasma enhanced chemical vapor deposition | BREWER SCIENCE INC. (US) | 2005-02-08 | — | — | US | disclosed |
| EP-1502292-A1 | POLYMERIC ANTIREFLECTIVE COATINGS DEPOSITED BY PLASMA ENHANCED CHEMICAL VAPOR DEPOSITION | Brewer Science, Inc. (US) | 2005-02-02 | — | — | EP | disclosed |
| US-20030224586-A1 | Polymeric antireflective coatings deposited by plasma enhanced chemical vapor deposition | BREWER SCIENCE, INC. | 2003-12-04 | — | — | US | disclosed |
| WO-2003094213-A1 | POLYMERIC ANTIREFLECTIVE COATINGS DEPOSITED BY PLASMA ENHANCED CHEMICAL VAPOR DEPOSITION | BREWER SCIENCE, INC. (US) | 2003-11-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240158390-A1 | OTHER HETEROAROMATIC COMPOUNDS HAVING ACTIVITY AGAINST RSV | MAVS, ZC3HAV1, RNASEH1 | PYCR1 119/4885DGAT1 3908/4885KDM1A 3249/4885 |
| US-11708369-B2 | Heteroaromatic compounds having activity against RSV | MAVS, ZC3HAV1, SARS1 | PYCR1 261/4885DGAT1 3731/4885KDM1A 3236/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.