Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1336142 | 0.92 | CNR2 (1.00) | CNR2CNR1 | |
| SCHEMBL1336062 | 0.88 | CNR2 (1.00) | CNR2CNR1 | |
| SCHEMBL1334504 | 0.87 | CNR2 (1.00) | CNR2CNR1 | |
| SCHEMBL1334490 | 0.86 | CNR2 (0.80) | CNR2CNR1 | |
| SCHEMBL1335127 | 0.85 | CNR2 (0.86) | CNR2CNR1 | |
| SCHEMBL1335125 | 0.85 | CNR2 (0.86) | CNR2CNR1 | |
| SCHEMBL1336168 | 0.85 | CNR2 (0.86) | CNR2CNR1 | |
| SCHEMBL1334940 | 0.85 | CNR2 (0.80) | CNR2CNR1 | |
| Hydrochloric Acid SCHEMBL1334513 | 0.84 | CNR2 (0.84) | CNR2CNR1 | |
| Hydrochloric Acid SCHEMBL1334516 | 0.84 | CNR2 (0.84) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12617776-B2 | Stable salt and crystal forms of 2-[3-({1-[2-(dimethylamino)ethyl]-2-(2,2-dimethylpropyl)-1H-1,3-benzodiazol-5-yl}sulfonyl)azetidin-1-yl]ethan-1-ol | ASKAT INC. (JP) | 2026-05-05 | — | — | US | claimed |
| US-20240352004-A1 | STABLE SALT AND CRYSTAL FORMS OF 2-[3-({1-[2-(DIMETHYLAMINO)ETHYL]-2-(2,2-DIMETHYLPROPYL)-1H-1,3-BENZODIAZOL-5-YL}SULFONYL)AZETIDIN-1-YL]ETHAN-1-OL | ASKAT INC. (JP) | 2024-10-24 | — | — | US | claimed |
| US-11964963-B2 | Stable salt and crystal forms of 2-[3-({1-[2-(dimethylamino)ethyl]-2-(2,2-dimethylpropyl)-1H-1,3-benzodiazol-5-yl}sulfonyl)azetidin-1-yl]ethan-1-ol | ASKAT INC. (JP) | 2024-04-23 | — | — | US | claimed |
| US-20230322737-A1 | STABLE SALT AND CRYSTAL FORMS OF 2-[3-({1-[2-(DIMETHYLAMINO)ETHYL]-2-(2,2-DIMETHYLPROPYL)-1H-1,3-BENZODIAZOL-5-YL}SULFONYL)AZETIDIN-1-YL]ETHAN-1-OL | ASKAT INC. (JP) | 2023-10-12 | — | — | US | claimed |
| EP-4244220-A1 | STABLE SALT AND CRYSTAL FORMS OF 2-[3-({1-[2-(DIMETHYLAMINO)ETHYL]-2-(2,2-DIMETHYLPROPYL)-1H-1,3-BENZODIAZOL-5-YL}SULFONYL)AZETIDIN-1-YL]ETHAN-1-OL | AskAt Inc. (JP) | 2023-09-20 | — | — | EP | claimed |
| WO-2022102713-A1 | STABLE SALT AND CRYSTAL FORMS OF 2-[3-({1-[2-(DIMETHYLAMINO)ETHYL]-2-(2,2-DIMETHYLPROPYL)-1H-1,3-BENZODIAZOL-5-YL}SULFONYL)AZETIDIN-1-YL]ETHAN-1-OL | ASKAT INC. (JP) | 2022-05-19 | — | — | WO | claimed |
| US-8653063-B2 | N-substituted saturated heterocyclic sulfone compounds with CB2 receptor agonistic activity | RAQUALIA PHARMA INC. (JP) | 2014-02-18 | — | — | US | claimed |
| US-20110281840-A1 | N-SUBSTITUTED SATURATED HETEROCYCLIC SULFONE COMPOUNDS WITH CB2 RECEPTOR AGONISTIC ACTIVITY | ASKAT INC. (JP) | 2011-11-17 | — | — | US | claimed |
| EP-2379533-A1 | N-SUBSTITUTED SATURATED HETEROCYCLIC SULFONE COMPOUNDS WITH CB2 RECEPTOR AGONISTIC ACTIVITY | RaQualia Pharma Inc (JP) | 2011-10-26 | — | — | EP | claimed |
| WO-2010084767-A1 | N-SUBSTITUTED SATURATED HETEROCYCLIC SULFONE COMPOUNDS WITH CB2 RECEPTOR AGONISTIC ACTIVITY | RAQUALIA PHARMA INC. (JP) | 2010-07-29 | — | — | WO | claimed |
| US-12617776-B2 | Stable salt and crystal forms of 2-[3-({1-[2-(dimethylamino)ethyl]-2-(2,2-dimethylpropyl)-1H-1,3-benzodiazol-5-yl}sulfonyl)azetidin-1-yl]ethan-1-ol | ASKAT INC. (JP) | 2026-05-05 | — | — | US | disclosed |
| US-12617776-B2 | Stable salt and crystal forms of 2-[3-({1-[2-(dimethylamino)ethyl]-2-(2,2-dimethylpropyl)-1H-1,3-benzodiazol-5-yl}sulfonyl)azetidin-1-yl]ethan-1-ol | ASKAT INC. (JP) | 2026-05-05 | — | — | US | disclosed |
| US-12617776-B2 | Stable salt and crystal forms of 2-[3-({1-[2-(dimethylamino)ethyl]-2-(2,2-dimethylpropyl)-1H-1,3-benzodiazol-5-yl}sulfonyl)azetidin-1-yl]ethan-1-ol | ASKAT INC. (JP) | 2026-05-05 | — | — | US | disclosed |
| US-20240352004-A1 | STABLE SALT AND CRYSTAL FORMS OF 2-[3-({1-[2-(DIMETHYLAMINO)ETHYL]-2-(2,2-DIMETHYLPROPYL)-1H-1,3-BENZODIAZOL-5-YL}SULFONYL)AZETIDIN-1-YL]ETHAN-1-OL | ASKAT INC. (JP) | 2024-10-24 | — | — | US | disclosed |
| US-20240352004-A1 | STABLE SALT AND CRYSTAL FORMS OF 2-[3-({1-[2-(DIMETHYLAMINO)ETHYL]-2-(2,2-DIMETHYLPROPYL)-1H-1,3-BENZODIAZOL-5-YL}SULFONYL)AZETIDIN-1-YL]ETHAN-1-OL | ASKAT INC. (JP) | 2024-10-24 | — | — | US | disclosed |
| US-20110281840-A1 | N-SUBSTITUTED SATURATED HETEROCYCLIC SULFONE COMPOUNDS WITH CB2 RECEPTOR AGONISTIC ACTIVITY | ASKAT INC. (JP) | 2011-11-17 | — | — | US | disclosed |
| US-20110281840-A1 | N-SUBSTITUTED SATURATED HETEROCYCLIC SULFONE COMPOUNDS WITH CB2 RECEPTOR AGONISTIC ACTIVITY | ASKAT INC. (JP) | 2011-11-17 | — | — | US | disclosed |
| US-20110281840-A1 | N-SUBSTITUTED SATURATED HETEROCYCLIC SULFONE COMPOUNDS WITH CB2 RECEPTOR AGONISTIC ACTIVITY | ASKAT INC. (JP) | 2011-11-17 | — | — | US | disclosed |
| EP-2379533-A1 | N-SUBSTITUTED SATURATED HETEROCYCLIC SULFONE COMPOUNDS WITH CB2 RECEPTOR AGONISTIC ACTIVITY | RaQualia Pharma Inc (JP) | 2011-10-26 | — | — | EP | disclosed |
| WO-2010084767-A1 | N-SUBSTITUTED SATURATED HETEROCYCLIC SULFONE COMPOUNDS WITH CB2 RECEPTOR AGONISTIC ACTIVITY | RAQUALIA PHARMA INC. (JP) | 2010-07-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110281840-A1 | N-SUBSTITUTED SATURATED HETEROCYCLIC SULFONE COMPOUNDS WITH CB2 RECEPTOR AGONISTIC ACTIVITY | CNR1, CNR2, NPSR1 | CNR2 2/4885CNR1 1/4885 |
| US-12617776-B2 | Stable salt and crystal forms of 2-[3-({1-[2-(dimethylamino)ethyl]-2-(2,2-dimethylpropyl)-1H-1,3-benzodiazol-5-yl}sulfonyl)azetidin-1-yl]ethan-1-ol | SLC5A1, ASIC1, SCNN1A | CNR2 2511/4885CNR1 2606/4885 |
| US-20230322737-A1 | STABLE SALT AND CRYSTAL FORMS OF 2-[3-({1-[2-(DIMETHYLAMINO)ETHYL]-2-(2,2-DIMETHYLPROPYL)-1H-1,3-BENZODIAZOL-5-YL}SULFONYL)AZETIDIN-1-YL]ETHAN-1-OL | CNR1, CNR2, TRPV1 | CNR2 2/4885CNR1 1/4885 |
| US-11964963-B2 | Stable salt and crystal forms of 2-[3-({1-[2-(dimethylamino)ethyl]-2-(2,2-dimethylpropyl)-1H-1,3-benzodiazol-5-yl}sulfonyl)azetidin-1-yl]ethan-1-ol | CNR1, CNR2, TRPV1 | CNR2 2/4885CNR1 1/4885 |
| US-20240352004-A1 | STABLE SALT AND CRYSTAL FORMS OF 2-[3-({1-[2-(DIMETHYLAMINO)ETHYL]-2-(2,2-DIMETHYLPROPYL)-1H-1,3-BENZODIAZOL-5-YL}SULFONYL)AZETIDIN-1-YL]ETHAN-1-OL | SLC5A1, CLIC1, SEM1 | CNR2 1660/4885CNR1 1425/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.