Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP3 | O14638 | 4/20 | 0.53 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 10/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 10/20 | 0.44 |
| ▸ | MIF | P14174 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8228630 | 0.85 | ENPP3 (0.58) | ENPP3ENPP1KMT2ASCN9ATP53 | |
| SCHEMBL8418313 | 0.83 | ENPP3 (0.56) | ENPP3ENPP1KMT2ASCN9ATP53 | |
| SCHEMBL13450985 | 0.81 | ENPP3 (0.53) | ENPP3ENPP1KMT2ASCN9ATP53 | |
| SCHEMBL12021934 | 0.81 | ENPP3 (0.53) | ENPP3ENPP1KMT2ASCN9ATP53 | |
| SCHEMBL8257975 | 0.80 | ENPP3 (0.56) | ENPP3ENPP1KMT2ASCN9ATP53 | |
| SCHEMBL8221289 | 0.78 | ENPP3 (0.50) | ENPP3ENPP1KMT2ASCN9ATP53 | |
| SCHEMBL8281113 | 0.78 | ENPP3 (0.56) | ENPP3ENPP1KMT2ASCN9ATP53 | |
| SCHEMBL12021820 | 0.77 | ENPP3 (0.53) | ENPP3ENPP1KMT2ASCN9ATP53 | |
| SCHEMBL14259170 | 0.77 | ENPP3 (0.53) | ENPP3ENPP1KMT2AESR2SCN9A | |
| SCHEMBL8221400 | 0.77 | ENPP3 (0.53) | ENPP3ENPP1KMT2ASCN9ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7709492-B2 | Pyrazolo-[4,3-e]-1,2,4-triazolo-[1,5-c]-pyrimidine adenosine A2a receptor antagonists | SCHERING CORPORATION (US) | 2010-05-04 | — | — | US | disclosed |