Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP3 | O14638 | 5/20 | 0.53 |
| ▸ | ENPP1 | P22413 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12021894 | 0.87 | ENPP3 (0.53) | ENPP3ENPP1KMT2ASCN9APOLB | |
| SCHEMBL8228630 | 0.85 | ENPP3 (0.58) | ENPP3ENPP1KMT2ASCN9APOLB | |
| SCHEMBL8418313 | 0.83 | ENPP3 (0.56) | ENPP3ENPP1KMT2ASCN9APOLB | |
| SCHEMBL14259170 | 0.81 | ENPP3 (0.53) | ENPP3ENPP1KMT2ASCN9APOLB | |
| SCHEMBL12021934 | 0.81 | ENPP3 (0.53) | ENPP3ENPP1KMT2ASCN9APOLB | |
| SCHEMBL13344879 | 0.81 | ENPP3 (0.53) | ENPP3ENPP1KMT2ASCN9APOLB | |
| SCHEMBL8257975 | 0.80 | ENPP3 (0.56) | ENPP3ENPP1KMT2ASCN9APOLB | |
| SCHEMBL8281113 | 0.78 | ENPP3 (0.56) | ENPP3ENPP1KMT2ASCN9ATP53 | |
| SCHEMBL8221289 | 0.78 | ENPP3 (0.50) | ENPP3ENPP1KMT2ASCN9APOLB | |
| SCHEMBL12021820 | 0.77 | ENPP3 (0.53) | ENPP3ENPP1KMT2ASCN9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1745047-B1 | PYRAZOLO[4,3-E]-1,2,4-TRIAZOLO[1,5-C]PYRIMIDINE ADENOSINE-A2A- RECEPTOR ANTAGONISTS | SCHERING CORP (US) | 2010-03-24 | — | — | EP | disclosed |