Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 8/20 | 0.55 |
| ▸ | NSD2 | O96028 | 1/20 | 0.48 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.48 |
| ▸ | PTPRC | P08575 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.44 |
| ▸ | CDC25B | P30305 | 2/20 | 0.42 |
| ▸ | PTPRF | P10586 | 1/20 | 0.42 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.41 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4278286 | 0.76 | CDC25B (0.57) | PTPN1NSD2HKDC1PTPRCMAPT | |
| SCHEMBL7912434 | 0.68 | PTPN1 (0.60) | PTPN1NSD2HKDC1PTPRCMAPT | |
| SCHEMBL7777406 | 0.68 | CTDSP1 (0.46) | PTPN1HKDC1MAPTKDM4EALDH1A1 | |
| SCHEMBL11585770 | 0.67 | ADORA2A (0.50) | NSD2PTPRCMAPTKDM4EALDH1A1 | |
| SCHEMBL10865783 | 0.66 | MEN1 (0.36) | NSD2PTPRCMAPTKDM4EALDH1A1 | |
| 4-Amino-[1,2]Naphthoquinone SCHEMBL422308 | 0.66 | PTPN1 (1.00) | PTPN1NSD2HKDC1PTPRCMAPT | |
| SCHEMBL5656918 | 0.66 | MEN1 (0.32) | PTPRCMAPTKDM4EALDH1A1CYP3A4 | |
| SCHEMBL9402069 | 0.66 | MAPT (0.51) | MAPTKDM4EALDH1A1CYP3A4HPGD | |
| SCHEMBL11872732 | 0.66 | — | — | |
| SCHEMBL10195777 | 0.66 | PTPN1 (0.61) | PTPN1NSD2HKDC1PTPRCMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2426212-A1 | Method for controlling NAD(P)/NAD(P)H ratio by oxidoreductase | Md Bioalpha Co., Ltd. (KR) | 2012-03-07 | — | — | EP | claimed |
| EP-2426212-A1 | Method for controlling NAD(P)/NAD(P)H ratio by oxidoreductase | Md Bioalpha Co., Ltd. (KR) | 2012-03-07 | — | — | EP | disclosed |
| US-20090215145-A1 | METHOD FOR CONTROLLING NAD(P)/NAD(P)H RATIO BY OXIDOREDUCTASE | MD BIOALPHA CO., LTD. (KR) | 2009-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090215145-A1 | METHOD FOR CONTROLLING NAD(P)/NAD(P)H RATIO BY OXIDOREDUCTASE | NQO1, NADK, ME2 | PTPN1 3820/4885NSD2 3169/4885HKDC1 1394/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.