Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | EGFR | P00533 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | FYN | P06241 | 2/20 | 0.36 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | MMP9 | P14780 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | MMP12 | P39900 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12648427 | 0.83 | TAAR1 (0.43) | GAATAAR1ALDH1A1MMP2KDM4E | |
| SCHEMBL31620229 | 0.79 | TAAR1 (0.42) | GAATAAR1LMNAALDH1A1EGFR | |
| SCHEMBL3061211 | 0.79 | TAAR1 (0.42) | GAATAAR1LMNAALDH1A1EGFR | |
| SCHEMBL1262234 | 0.77 | GABRA1 (0.39) | GAATAAR1LMNAALDH1A1EGFR | |
| SCHEMBL8053878 | 0.77 | TAAR1 (0.45) | GAATAAR1LMNAALDH1A1EGFR | |
| SCHEMBL27324557 | 0.77 | CES2 (0.39) | GAATAAR1LMNAALDH1A1EGFR | |
| SCHEMBL7706281 | 0.74 | TAAR1 (0.38) | GAATAAR1ALDH1A1CA2HPGD | |
| SCHEMBL23841325 | 0.72 | GABRA1 (0.45) | GAATAAR1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL6553054 | 0.72 | MAPT (0.36) | GAATAAR1LMNAALDH1A1EGFR | |
| SCHEMBL15107553 | 0.72 | ANO1 (0.41) | GAATAAR1LMNAALDH1A1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010071846-A2 | COMPOUNDS FOR TREATING NEUROPSYCHIATRIC CONDITIONS | AFRAXIS, INC. (US) | 2010-06-24 | — | — | WO | disclosed |