Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | EDNRA | P25101 | 3/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2826386 | 0.87 | ACMSD (0.39) | ACMSDNPC1RAB9ALMNACYP2D6 | |
| SCHEMBL2826388 | 0.87 | ACMSD (0.39) | ACMSDNPC1RAB9ALMNACYP2D6 | |
| SCHEMBL637611 | 0.86 | ACMSD (0.37) | ACMSDNPC1RAB9ALMNACYP2D6 | |
| SCHEMBL637610 | 0.86 | ACMSD (0.37) | ACMSDNPC1RAB9ALMNACYP2D6 | |
| SCHEMBL13345648 | 0.85 | TRPM8 (0.36) | NPC1RAB9ALMNACYP2D6CYP2C19 | |
| SCHEMBL2825379 | 0.84 | MAPK1 (0.45) | ACMSDNPC1RAB9ALMNAL3MBTL1 | |
| SCHEMBL2825383 | 0.84 | MAPK1 (0.45) | ACMSDNPC1RAB9ALMNAL3MBTL1 | |
| SCHEMBL636241 | 0.84 | ACMSD (0.37) | ACMSDNPC1RAB9ALMNACYP2D6 | |
| SCHEMBL636242 | 0.84 | ACMSD (0.37) | ACMSDNPC1RAB9ALMNACYP2D6 | |
| SCHEMBL6032767 | 0.82 | HCRTR1 (0.37) | ACMSDNPC1RAB9ALMNACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010070452-A1 | FUSED IMIDAZOLE CARBOXAMIDES AS TRPV3 MODULATORS | GLENMARK PHARMACEUTICALS, S.A. (CH) | 2010-06-24 | — | — | WO | disclosed |