Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 8/20 | 0.59 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.59 |
| ▸ | MPC2 | O95563 | 1/20 | 0.59 |
| ▸ | CA2 | P00918 | 2/20 | 0.58 |
| ▸ | FFAR1 | O14842 | 7/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.48 |
| ▸ | PPARA | Q07869 | 3/20 | 0.48 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | CYP4B1 | P13584 | 1/20 | 0.47 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.47 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.47 |
| ▸ | CYP2A7 | P20853 | 1/20 | 0.47 |
| ▸ | CYP3A7 | P24462 | 1/20 | 0.47 |
| ▸ | CYP2F1 | P24903 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3798362 | 0.88 | PPARG (0.60) | PPARGCYP2C8CYP2C9MPC2CA2 | |
| SCHEMBL3797980 | 0.88 | FFAR1 (0.61) | PPARGCYP2C8CYP2C9MPC2CA2 | |
| SCHEMBL8313625 | 0.82 | FFAR1 (0.61) | PPARGCYP2C8CYP2C9MPC2FFAR1 | |
| SCHEMBL5905550 | 0.80 | FFAR1 (0.59) | PPARGCYP2C8CYP2C9MPC2FFAR1 | |
| SCHEMBL12631758 | 0.79 | PPARG (0.59) | PPARGCYP2C8CYP2C9MPC2CA2 | |
| SCHEMBL1247602 | 0.78 | PPARG (0.66) | PPARGCYP2C8CYP2C9MPC2CA2 | |
| SCHEMBL3840336 | 0.78 | FFAR1 (0.65) | PPARGCYP2C8CYP2C9MPC2CA2 | |
| SCHEMBL8312939 | 0.78 | MAPT (0.69) | PPARGCYP2C8CYP2C9MPC2FFAR1 | |
| SCHEMBL8314990 | 0.77 | MAPT (0.60) | PPARGCYP2C8CYP2C9MPC2FFAR1 | |
| SCHEMBL6931105 | 0.76 | PPARG (0.70) | PPARGCYP2C8CYP2C9MPC2CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7718682-B2 | Heterocyclic analogs of diphenylethylene compounds | THERACOS, INC. (US) | 2010-05-18 | — | — | US | disclosed |
| US-7718682-B2 | Heterocyclic analogs of diphenylethylene compounds | THERACOS, INC. (US) | 2010-05-18 | — | — | US | disclosed |
| US-20080293949-A1 | Novel heterocyclic analogs of diphenylethylene compounds | THERACOS, INC. (US) | 2008-11-27 | — | — | US | disclosed |
| US-20080293949-A1 | Novel heterocyclic analogs of diphenylethylene compounds | THERACOS, INC. (US) | 2008-11-27 | — | — | US | disclosed |
| US-7407978-B2 | Heterocyclic analogs of diphenylethylene compounds | THERACOS, INC. (US) | 2008-08-05 | — | — | US | disclosed |
| US-7407978-B2 | Heterocyclic analogs of diphenylethylene compounds | THERACOS, INC. (US) | 2008-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293949-A1 | Novel heterocyclic analogs of diphenylethylene compounds | FFAR2, FFAR4, GPR119 | PPARG 10/4885CYP2C8 1831/4885CYP2C9 1567/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.