Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.49 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 4/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | GHSR | Q92847 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27932708 | 0.82 | NOTUM (0.49) | ALDH1A1KDM4EMAPK1PTPN1L3MBTL1 | |
| SCHEMBL13347571 | 0.79 | NOTUM (0.46) | ALDH1A1KDM4EMAPK1PTPN1NOTUM | |
| SCHEMBL16051759 | 0.78 | NOTUM (0.42) | ALDH1A1KDM4EMAPK1PTPN1NOTUM | |
| SCHEMBL13347701 | 0.78 | HCRTR1 (0.44) | ALDH1A1KDM4EMAPK1PTPN1NOTUM | |
| SCHEMBL23667579 | 0.78 | KDM4E (0.57) | ALDH1A1KDM4EMAPK1NOTUMTDP1 | |
| SCHEMBL6850771 | 0.78 | KDM4E (0.57) | ALDH1A1KDM4EMAPK1FGFR1NOTUM | |
| SCHEMBL8216643 | 0.78 | NOTUM (0.53) | ALDH1A1KDM4EMAPK1PTPN1NOTUM | |
| SCHEMBL8114245 | 0.78 | NOTUM (0.45) | ALDH1A1KDM4EMAPK1PTPN1NOTUM | |
| SCHEMBL2188351 | 0.78 | NLRP3 (0.45) | ALDH1A1KDM4EMAPK1PTPN1NOTUM | |
| SCHEMBL5756029 | 0.78 | PTPN1 (0.49) | ALDH1A1POLBKDM4EMAPK1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7737154-B2 | CRF receptor antagonists and methods relating thereto | SMITHKLINE BEECHAM (CORK) LIMITED (IE) | 2010-06-15 | — | — | US | disclosed |