Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.38 |
| ▸ | PRCP | P42785 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.36 |
| ▸ | GBA1 | P04062 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1334994 | 1.00 | SLC6A2 (0.47) | SLC6A2ADRA1AHTR2BSLC6A3TSHR | |
| SCHEMBL1332817 | 1.00 | SLC6A2 (0.47) | SLC6A2ADRA1AHTR2BSLC6A3TSHR | |
| SCHEMBL1334838 | 1.00 | SLC6A2 (0.47) | SLC6A2ADRA1AHTR2BSLC6A3TSHR | |
| SCHEMBL1333855 | 0.82 | CHRNA7 (0.35) | SLC6A2ADRA1AHTR2BSLC6A3METTL3 | |
| SCHEMBL25331754 | 0.82 | MDM2 (0.36) | TSHRCYP2C19METTL3MEN1KMT2A | |
| SCHEMBL25331394 | 0.82 | MDM2 (0.36) | TSHRCYP2C19METTL3MEN1KMT2A | |
| SCHEMBL25331397 | 0.82 | MDM2 (0.36) | TSHRCYP2C19METTL3MEN1KMT2A | |
| SCHEMBL1334868 | 0.82 | CHRNA7 (0.35) | SLC6A2ADRA1AHTR2BSLC6A3METTL3 | |
| SCHEMBL1333460 | 0.82 | CHRNA7 (0.35) | SLC6A2ADRA1AHTR2BSLC6A3METTL3 | |
| SCHEMBL25330400 | 0.82 | MDM2 (0.36) | TSHRCYP2C19METTL3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018116285-A1 | SUBSTITUTED MORPHOLINE DERIVATIVES AS ROR GAMMA MODULATORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2018-06-28 | — | — | WO | disclosed |
| US-20110281854-A1 | MORPHOLINE COMPOUNDS | PFIZER INC | 2011-11-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110281854-A1 | MORPHOLINE COMPOUNDS | REN, MC2R, NR3C2 | SLC6A2 966/4885ADRA1A 32/4885HTR2B 459/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.