⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9337730 | 0.97 | — | — | |
| Trifluoroacetic Acid SCHEMBL3631442 | 0.87 | PKM (0.42) | — | |
| SCHEMBL6648809 | 0.85 | — | — | |
| SCHEMBL6961568 | 0.83 | — | — | |
| SCHEMBL15319 | 0.83 | — | — | |
| SCHEMBL29586735 | 0.83 | CA2 (0.50) | — | |
| SCHEMBL17100538 | 0.83 | CA2 (0.56) | — | |
| Ammonia Solution, Strong SCHEMBL29137284 | 0.83 | CA2 (0.40) | — | |
| SCHEMBL2124443 | 0.83 | CA2 (0.45) | — | |
| SCHEMBL1919228 | 0.81 | CA2 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2786990-B1 | 2-AMINATED METHYLENE OR 2-ESTERIFIED METHYLENE TANSHINONE DERIVATIVES, AND PREPARATION METHOD AND APPLICATION THEREOF | HANGZHOU BENSHENG PHARMACEUTICAL CO LTD (CN) | 2018-08-08 | — | — | EP | claimed |
| US-9328083-B2 | 2-aminated methylene or 2-esterified methylene tanshinone derivatives, and preparation method and application thereof | HANGZHOU BENSHENG PHARMACEUTICAL CO., LTD. (CN) | 2016-05-03 | — | — | US | claimed |
| US-20150126552-A1 | 2-AMINATED METHYLENE OR 2-ESTERIFIED METHYLENE TANSHINONE DERIVATIVES, AND PREPARATION METHOD AND APPLICATION THEREOF | HANGZHOU BENSHENG PHARMACEUTICAL CO., LTD. (CN) | 2015-05-07 | — | — | US | claimed |
| EP-2786990-A1 | 2-AMINATED METHYLENE OR 2-ESTERIFIED METHYLENE TANSHINONE DERIVATIVES, AND PREPARATION METHOD AND APPLICATION THEREOF | Hangzhou Bensheng Pharmaceutical Co., Ltd. (CN) | 2014-10-08 | — | — | EP | claimed |
| EP-0079050-B1 | 4-AROYLIMIDAZOLIDIN-2-ONES | MERRELL DOW PHARMACEUTICALS INC. (US) | 1987-04-08 | — | — | EP | claimed |
| EP-0079050-A1 | 4-Aroylimidazolidin-2-ones | MERRELL DOW PHARMACEUTICALS INC. (US) | 1983-05-18 | — | — | EP | claimed |
| EP-4667479-A1 | POLYPHOSPHORYLATED NUCLEOSIDE, PHOSPHATE-ACTIVATED NUCLEOTIDE USED FOR SYNTHESIS OF POLYPHOSPHORYLATED NUCLEOSIDE AND METHOD FOR SYNTHESIS OF SAME, AND METHOD FOR SYNTHESIS OF POLYPHOSPHORYLATED NUCLEOSIDE USING PHOSPHATE-ACTIVATED NUCLEOTIDE | Natias Inc. (JP) | 2025-12-24 | — | — | EP | disclosed |
| US-20250066368-A1 | DNA POLYMERASE THETA INHIBITOR AND USE THEREOF | SHANGHAI APEIRON THERAPEUTICS COMPANY LIMITED (CN) | 2025-02-27 | — | — | US | disclosed |
| EP-4455129-A1 | DNA POLYMERASE THETA INHIBITOR AND USE THEREOF | Shanghai Apeiron Therapeutics Company Limited (CN) | 2024-10-30 | — | — | EP | disclosed |
| WO-2024153173-A1 | AROMATIC ACETYLENE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 浙江海正药业股份有限公司 | 2024-07-25 | — | — | WO | disclosed |
| WO-2023125918-A1 | DNA POLYMERASE THETA INHIBITOR AND USE THEREOF | 上海湃隆生物科技有限公司 | 2023-07-06 | — | — | WO | disclosed |
| CN-115825414-A | Blood or urine metabolic marker and application thereof in endometrial cancer early screening | 中国医学科学院北京协和医院 | 2023-03-21 | — | — | CN | disclosed |
| US-20220380347-A1 | INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF | Pardes Biosciences, Inc. | 2022-12-01 | — | — | US | disclosed |
| EP-0090405-B1 | NOVEL AZOLE DINUCLEOTIDE COMPOUNDS AND METHODS FOR THEIR PRODUCTION | BRIGHAM YOUNG UNIVERSITY (US) | 1986-06-25 | — | — | EP | disclosed |
| US-4594415-A | Viricides | ROBINS ROLAND K (US) | 1986-06-10 | — | — | US | disclosed |
| US-4544741-A | Azole dinucleotide compounds and methods for their production | BRIGHAM YOUNG UNIVERSITY, PROVO, UT., A NONPROFIT CORP. OF UT | 1985-10-01 | — | — | US | disclosed |
| US-4476301-A | Oligonucleotides, a process for preparing the same and their application as mediators of the action of interferon | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 1984-10-09 | — | — | US | disclosed |
| US-4410540-A | Cardiotonic 4-aroylimidazolidin-2-ones | MERRELL DOW PHARMACEUTICALS INC. (US) | 1983-10-18 | — | — | US | disclosed |
| EP-0090405-A1 | Novel azole dinucleotide compounds and methods for their production | BRIGHAM YOUNG UNIVERSITY (US) | 1983-10-05 | — | — | EP | disclosed |
| EP-0079050-A1 | 4-Aroylimidazolidin-2-ones | MERRELL DOW PHARMACEUTICALS INC. (US) | 1983-05-18 | — | — | EP | disclosed |