Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | OGA | O60502 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GCK | P35557 | 1/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.31 |
| ▸ | SLC2A2 | P11168 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2660204 | 0.92 | ALDH1A1 (0.42) | ALDH1A1LMNAHPGDSMN1; SMN2KMT2A | |
| SCHEMBL2660368 | 0.89 | ALDH1A1 (0.44) | ALDH1A1LMNAHPGDSMN1; SMN2KMT2A | |
| SCHEMBL2659654 | 0.83 | ALDH1A1 (0.38) | ALDH1A1SMN1; SMN2KMT2AOGAL3MBTL1 | |
| SCHEMBL2971603 | 0.83 | ALDH1A1 (0.43) | ALDH1A1LMNAHPGDSMN1; SMN2KMT2A | |
| SCHEMBL2659475 | 0.83 | ALDH1A1 (0.37) | ALDH1A1LMNASMN1; SMN2KMT2AOGA | |
| SCHEMBL2660486 | 0.82 | ALDH1A1 (0.42) | ALDH1A1LMNAHPGDSMN1; SMN2KMT2A | |
| SCHEMBL13203318 | 0.81 | HSD17B10 (0.45) | ALDH1A1LMNAHPGDSMN1; SMN2KMT2A | |
| SCHEMBL2659787 | 0.80 | ALDH1A1 (0.36) | ALDH1A1HPGDSMN1; SMN2OGAL3MBTL1 | |
| SCHEMBL2660698 | 0.80 | ALDH1A1 (0.35) | ALDH1A1LMNAHPGDSMN1; SMN2KMT2A | |
| SCHEMBL2660658 | 0.80 | ALDH1A1 (0.36) | ALDH1A1LMNASMN1; SMN2OGAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100137610-A1 | Indole compound | YASUMA TSUNEO | 2010-06-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137610-A1 | Indole compound | GCKR, GPR119, SLC5A1 | ALDH1A1 376/4885LMNA 4727/4885HPGD 1786/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.