Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6560519 | 0.79 | GABRA1 (0.42) | GABRA1GABRB2KDM4EPOLBSMN1; SMN2 | |
| SCHEMBL23863910 | 0.78 | GABRA1 (0.39) | GABRA1GABRB2KDM4EPOLBSMN1; SMN2 | |
| SCHEMBL487712 | 0.78 | UHRF1 (0.46) | GABRA1GABRB2KDM4EPOLBSMN1; SMN2 | |
| SCHEMBL8430518 | 0.77 | — | — | |
| SCHEMBL17000195 | 0.76 | POLB (0.44) | GABRA1GABRB2KDM4EPOLBSMN1; SMN2 | |
| SCHEMBL18458630 | 0.76 | GABRA1 (0.48) | GABRA1GABRB2KDM4EPOLBSMN1; SMN2 | |
| SCHEMBL10159790 | 0.76 | RECQL (0.57) | GABRA1GABRB2KDM4EPOLBSMN1; SMN2 | |
| SCHEMBL12120626 | 0.76 | GABRA1 (0.40) | GABRA1GABRB2KDM4EPOLBSMN1; SMN2 | |
| SCHEMBL17000172 | 0.76 | GABRA1 (0.40) | GABRA1GABRB2KDM4EPOLBSMN1; SMN2 | |
| SCHEMBL831023 | 0.76 | NOS3 (0.62) | GABRA1GABRB2KDM4EPOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10451604-B2 | Methods of measuring hydrogen sulfide concentrations in reservoir fluids | SHELL OIL COMPANY (US) | 2019-10-22 | — | — | US | disclosed |
| US-20180045705-A1 | METHODS OF MEASURING HYDROGEN SULFIDE CONCENTRATIONS IN RESERVOIR FLUIDS | SHELL OIL COMPANY | 2018-02-15 | — | — | US | disclosed |
| EP-1539980-B1 | LIBRARY OF COMPLEXES COMPRISING SMALL NON-PEPTIDE MOLECULES AND DOUBLE-STRANDED OLIGONUCLEOTIDES IDENTIFYING THE MOLECULES | NUEVOLUTION AS (DK) | 2016-02-17 | — | — | EP | disclosed |
| US-9121110-B2 | Quasirandom structure and function guided synthesis methods | NUEVOLUTION A/S (DK) | 2015-09-01 | — | — | US | disclosed |
| US-7727713-B2 | Templated molecules and methods for using such molecules | NUEVOLUTION A/S (DK) | 2010-06-01 | — | — | US | disclosed |
| EP-2175019-A2 | Quasirandom structure and function guided synthesis methods | Nuevolution A/S (DK) | 2010-04-14 | — | — | EP | disclosed |
| US-20080193983-A1 | Quasirandom Structure and Function Guided Synthesis Methods | NUEVOLUTION A/S (DK) | 2008-08-14 | — | — | US | disclosed |
| EP-1402024-B1 | TEMPLATED MOLECULES AND METHODS FOR USING SUCH MOLECULES | NUEVOLUTION AS (DK) | 2007-08-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080193983-A1 | Quasirandom Structure and Function Guided Synthesis Methods | PARN, POLN, NCL | GABRA1 2657/4885GABRB2 1702/4885KDM4E 4797/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.