Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 5/20 | 0.57 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.55 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.55 |
| ▸ | NPY1R | P25929 | 1/20 | 0.55 |
| ▸ | NTSR1 | P30989 | 6/20 | 0.55 |
| ▸ | NTSR2 | O95665 | 4/20 | 0.54 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.54 |
| ▸ | REN | P00797 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16386324 | 1.00 | OPRD1 (0.57) | OPRD1OPRM1OPRK1NPY1RNTSR1 | |
| SCHEMBL10305285 | 0.97 | OPRD1 (0.55) | OPRD1OPRM1OPRK1NPY1RNTSR1 | |
| SCHEMBL12801808 | 0.91 | OPRD1 (0.47) | OPRD1OPRM1OPRK1NPY1RNTSR1 | |
| SCHEMBL12801453 | 0.88 | NPY1R (0.58) | OPRD1OPRM1OPRK1NPY1RNTSR1 | |
| SCHEMBL13315201 | 0.87 | NPY1R (0.53) | OPRD1OPRM1OPRK1NPY1RNTSR1 | |
| SCHEMBL10305352 | 0.87 | NTSR1 (0.65) | OPRD1OPRM1OPRK1NTSR1NTSR2 | |
| SCHEMBL12801534 | 0.86 | NPY1R (0.63) | OPRD1OPRM1OPRK1NPY1RNTSR1 | |
| SCHEMBL13315205 | 0.85 | NPY1R (0.56) | OPRD1OPRM1OPRK1NPY1RNTSR1 | |
| SCHEMBL14757595 | 0.85 | OPRD1 (0.66) | OPRD1OPRM1OPRK1NTSR1NTSR2 | |
| SCHEMBL16386378 | 0.84 | NPY1R (0.56) | OPRD1OPRM1OPRK1NPY1RNTSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100143250-A1 | COMPOUNDS FOR THE DIAGNOSIS OF APOPTOSIS | GUERBET (FR) | 2010-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100143250-A1 | COMPOUNDS FOR THE DIAGNOSIS OF APOPTOSIS | TPX2, VIP, BAX | OPRD1 3632/4885OPRM1 4403/4885OPRK1 2788/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.