Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 2/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31365939 | 0.88 | L3MBTL1 (0.57) | KDM4EEPHX2NPC1RAB9A | |
| SCHEMBL8515103 | 0.87 | KDM4E (0.49) | KDM4EMAPK1NAMPTEPHX2KDM4C | |
| SCHEMBL8031999 | 0.86 | MAPK1 (0.64) | POLBKDM4EMAPK1HDAC1 | |
| SCHEMBL16688446 | 0.85 | MAPK1 (0.61) | POLBKDM4EMAPK1NAMPTHDAC1 | |
| SCHEMBL12364920 | 0.84 | EPHX2 (0.60) | KDM4ENAMPTEPHX2NPC1RAB9A | |
| SCHEMBL14000504 | 0.84 | KDM4E (0.52) | KDM4EMAPK1EPHX2KDM4CNPC1 | |
| SCHEMBL12364931 | 0.83 | KDM4E (0.46) | KDM4EMAPK1NAMPTEPHX2KDM4C | |
| SCHEMBL8516388 | 0.83 | KDM4E (0.58) | POLBKDM4ENAMPTEPHX2KDM4C | |
| SCHEMBL8515153 | 0.83 | KDM4E (0.58) | POLBKDM4ENAMPTEPHX2KDM4C | |
| SCHEMBL8513622 | 0.83 | KDM4E (0.58) | POLBKDM4ENAMPTEPHX2KDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE46171-E1 | Functional biopolymer modification reagents and uses thereof | SOLULINK, INCORPORATED (US) | 2016-10-04 | — | — | US | disclosed |
| US-7732628-B2 | Such as 4-[8-(2-cyanoethyl-N,N-diisopropylphosphoramidyloxy)-2-aza-1-oxooct-1-yl]benzaldehyde, 4-[8-(2-cyanoethyl-N,N-diisopropylphosphoramidyloxy)-2-aza-1-oxooct-1-yl]acetophenone; for incorporation into oligonucleotides during immobilization and conjugation of biopolymers in solid phase synthesis | SOLULINK INCORPORATED (US) | 2010-06-08 | — | — | US | disclosed |