Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP7 | P09237 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | MMP12 | P39900 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16688446 | 0.99 | MAPK1 (0.61) | MAPK1CYP1A2CYP2C9CYP2C19HDAC6 | |
| SCHEMBL14000504 | 0.87 | KDM4E (0.52) | MAPK1HDAC6KDM4EALDH1A1HDAC1 | |
| SCHEMBL13349296 | 0.86 | POLB (0.50) | MAPK1POLBKDM4EHDAC1 | |
| SCHEMBL31365939 | 0.85 | L3MBTL1 (0.57) | KDM4EALDH1A1CA2SMN1; SMN2 | |
| SCHEMBL8515103 | 0.85 | KDM4E (0.49) | MAPK1CYP1A2KDM4EHDAC1 | |
| SCHEMBL12553844 | 0.83 | FOLH1 (0.74) | FOLH1 | |
| SCHEMBL9829017 | 0.82 | MAPK1 (0.69) | MAPK1CYP1A2CYP2C9CYP2C19HDAC6 | |
| SCHEMBL10099585 | 0.82 | MAPK1 (0.69) | MAPK1CYP1A2CYP2C9CYP2C19HDAC6 | |
| SCHEMBL12364920 | 0.82 | EPHX2 (0.60) | KDM4ECA2SMN1; SMN2 | |
| SCHEMBL13494941 | 0.81 | FOLH1 (0.74) | FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0984791-A1 | TERNARY LIGAND COMPLEXES USEFUL AS RADIOPHARMACEUTICALS | Du Pont Pharmaceuticals Company (US) | 2000-03-15 | — | — | EP | claimed |
| WO-1998053858-A1 | TERNARY LIGAND COMPLEXES USEFUL AS RADIOPHARMACEUTICALS | DU PONT PHARMACEUTICALS COMPANY (US) | 1998-12-03 | — | — | WO | claimed |
| EP-0984791-A1 | TERNARY LIGAND COMPLEXES USEFUL AS RADIOPHARMACEUTICALS | Du Pont Pharmaceuticals Company (US) | 2000-03-15 | — | — | EP | disclosed |
| WO-1998053858-A1 | TERNARY LIGAND COMPLEXES USEFUL AS RADIOPHARMACEUTICALS | DU PONT PHARMACEUTICALS COMPANY (US) | 1998-12-03 | — | — | WO | disclosed |