Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METTL3 | Q86U44 | 1/20 | 0.35 |
| ▸ | SLC5A2 | P31639 | 2/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13349641 | 0.90 | METTL3 (0.38) | METTL3SLC5A2EGFR | |
| SCHEMBL13349642 | 0.88 | METTL3 (0.34) | METTL3 | |
| SCHEMBL13349622 | 0.86 | METTL3 (0.34) | METTL3SLC5A2EGFR | |
| SCHEMBL13316678 | 0.85 | METTL3 (0.35) | METTL3SLC5A2EGFR | |
| SCHEMBL13349623 | 0.83 | — | — | |
| SCHEMBL13349640 | 0.82 | METTL3 (0.40) | METTL3SLC5A2EGFR | |
| SCHEMBL13349627 | 0.79 | METTL3 (0.38) | METTL3EGFR | |
| SCHEMBL13349605 | 0.79 | METTL3 (0.36) | METTL3SLC5A2EGFR | |
| SCHEMBL13349624 | 0.73 | — | — | |
| SCHEMBL13316679 | 0.73 | METTL3 (0.32) | METTL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7745459-B2 | Quinolizinone compound and use thereof as HIV integrase inhibitor | JAPAN TOBACCO INC. (JP) | 2010-06-29 | — | — | US | disclosed |