Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METTL3 | Q86U44 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 6/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SLC5A2 | P31639 | 2/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.32 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.32 |
| ▸ | CTSA | P10619 | 1/20 | 0.32 |
| ▸ | CASR | P41180 | 1/20 | 0.32 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.31 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13349640 | 0.90 | METTL3 (0.40) | METTL3EGFRPOLBNPC1RAB9A | |
| SCHEMBL13349643 | 0.90 | METTL3 (0.35) | METTL3EGFRSLC5A2 | |
| SCHEMBL13316678 | 0.90 | METTL3 (0.35) | METTL3EGFRCSF1RSLC5A2CASR | |
| SCHEMBL13349627 | 0.87 | METTL3 (0.38) | METTL3EGFRPOLBCSF1RMEN1 | |
| SCHEMBL13349605 | 0.87 | METTL3 (0.36) | METTL3EGFRPOLBCSF1RMEN1 | |
| SCHEMBL13349598 | 0.81 | CXCR2 (0.32) | METTL3CXCR2 | |
| SCHEMBL13349642 | 0.79 | METTL3 (0.34) | METTL3CSF1RSLC16A3SLC16A1 | |
| SCHEMBL13349622 | 0.77 | METTL3 (0.34) | METTL3EGFRPOLBCSF1RMEN1 | |
| SCHEMBL13316673 | 0.77 | PDE10A (0.39) | METTL3EGFRCSF1RMEN1KMT2A | |
| SCHEMBL13316679 | 0.76 | METTL3 (0.32) | METTL3CSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7745459-B2 | Quinolizinone compound and use thereof as HIV integrase inhibitor | JAPAN TOBACCO INC. (JP) | 2010-06-29 | — | — | US | disclosed |