Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.44 |
| ▸ | QPCT | Q16769 | 1/20 | 0.44 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 6/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13097137 | 0.85 | NAMPT (0.48) | NAMPTRAB9AHRH3QPCTQPCTL | |
| SCHEMBL13097136 | 0.78 | ALDH1A1 (0.54) | NAMPTRAB9A | |
| SCHEMBL13106512 | 0.78 | MAPT (0.51) | NAMPTRAB9AHRH3PIK3CAPIK3CD | |
| SCHEMBL21814291 | 0.77 | NAMPT (0.54) | NAMPTHRH3BRD4PIK3CAPIK3CD | |
| SCHEMBL3087361 | 0.75 | HRH3 (0.78) | HRH3 | |
| SCHEMBL21814274 | 0.73 | HRH3 (0.53) | HRH3PIK3CAPIK3CD | |
| SCHEMBL25662665 | 0.73 | HRH3 (0.53) | NAMPTHRH3PIK3CAPIK3CD | |
| SCHEMBL21814257 | 0.72 | NAMPT (0.50) | NAMPTRAB9AHRH3BRD4KMT2A | |
| SCHEMBL21814260 | 0.71 | HRH3 (0.51) | HRH3PIK3CAPIK3CD | |
| SCHEMBL29377558 | 0.71 | HRH3 (0.51) | HRH3PIK3CAPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2194044-A1 | QUINOLONE DERIVATIVE | Astellas Pharma Inc. (JP) | 2010-06-09 | — | — | EP | disclosed |