Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | RORC | P51449 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.45 |
| ▸ | NAAA | Q02083 | 2/20 | 0.45 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13097139 | 0.86 | NAMPT (0.55) | ALDH1A1KDM4ELMNAHTTOPRK1 | |
| SCHEMBL13097138 | 0.85 | KDM4E (0.43) | ALDH1A1KDM4ELMNAHTTTP53 | |
| SCHEMBL13097137 | 0.83 | NAMPT (0.48) | NAMPTRAB9A | |
| SCHEMBL13106512 | 0.83 | MAPT (0.51) | MAPTNAMPTRAB9A | |
| SCHEMBL13097133 | 0.82 | ALDH1A1 (0.53) | ALDH1A1KDM4ELMNAOPRK1RORC | |
| SCHEMBL13097143 | 0.82 | HRH3 (0.44) | ALDH1A1KDM4ELMNAHTTRORC | |
| SCHEMBL13097116 | 0.81 | GRIN2D (0.49) | ALDH1A1HTTTP53SMN1; SMN2RORC | |
| SCHEMBL13097639 | 0.80 | CYP2D6 (0.66) | KDM4ELMNAHTTMAPTRAB9A | |
| SCHEMBL13349840 | 0.78 | NAMPT (0.46) | NAMPTRAB9A | |
| SCHEMBL2195099 | 0.78 | YAP1 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8367702-B2 | Quinolone derivative | ASTELLAS PHARMA INC. (JP) | 2013-02-05 | — | — | US | disclosed |
| US-20100256113-A1 | QUINOLONE DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2010-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100256113-A1 | QUINOLONE DERIVATIVE | NQO1, NQO2, NADK | ALDH1A1 524/4885KDM4E 1769/4885LMNA 2595/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.