SCHEMBL13350221

SCHEMBL13350221

CCCC(C)(C)Oc1cccc(OC(=O)c2ccccc2)c1

nearest known ligand 0.54

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 10/20 0.48
▸ MAPT P10636 4/20 0.48
▸ TDP1 Q9NUW8 3/20 0.48
▸ L3MBTL1 Q9Y468 1/20 0.48
▸ MEN1 O00255 1/20 0.47
▸ ESR1 P03372 2/20 0.45
▸ ESR2 Q92731 2/20 0.45
▸ ALDH1A1 P00352 2/20 0.43
▸ LMNA P02545 1/20 0.42
▸ PKM P14618 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14473537 0.89 KMT2A (0.48) KMT2AMAPTTDP1L3MBTL1MEN1
SCHEMBL12808314 0.89 KMT2A (0.50) KMT2AMAPTTDP1L3MBTL1MEN1
SCHEMBL14457304 0.87 KMT2A (0.46) KMT2AMAPTTDP1L3MBTL1MEN1
SCHEMBL13894564 0.83 KMT2A (0.50) KMT2AMAPTTDP1L3MBTL1MEN1
SCHEMBL260757 0.83 TDP1 (0.55) KMT2AMAPTTDP1L3MBTL1MEN1
SCHEMBL11659680 0.81 PPARA (0.39) KMT2A
SCHEMBL1785471 0.79 KMT2A (0.69) KMT2AMAPTTDP1L3MBTL1MEN1
SCHEMBL825441 0.78 KMT2A (0.50) KMT2AMAPTTDP1L3MBTL1MEN1
SCHEMBL12750157 0.77 KMT2A (0.68) KMT2AMAPTTDP1L3MBTL1MEN1
SCHEMBL12341608 0.77 LMNA (0.62) KMT2AMAPTTDP1L3MBTL1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1937790-B1 FLAME RETARDANT POLYSULFONE BLENDS SABIC INNOVATIVE PLASTICS IP (NL) 2010-06-30 — — EP disclosed
WO-2009006167-A1 RECYCLABLE MULTILAYER THERMOPLASTIC FILMS AND METHODS OF MAKING SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2009-01-08 — — WO disclosed
WO-2008091253-A1 HIGH HEAT ELECTRICAL CONNECTORS SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2008-07-31 — — WO disclosed
US-20070293626-A1 Polyamide blend compositions CITIBANK, N.A., AS COLLATERAL AGENT 2007-12-20 — — US disclosed
US-20070197700-A1 Release agent for transparent polymide blends GENERAL ELECTRIC COMPANY 2007-08-23 — — US disclosed
WO-2007078788-A2 FOOD SERVICE ARTICLES OF MANUFACTURE COMPRISING HIGH TEMPERATURE POLYMERS GENERAL ELECTRIC COMPANY (US) 2007-07-12 — — WO disclosed
WO-2007075365-A2 ANNULAR OR TUBULAR SHAPED ARTICLES OF NOVEL POLYMER BLENDS GENERAL ELECTRIC COMPANY (US) 2007-07-05 — — WO disclosed
US-20070149629-A1 Expanded and expandable high glass transition temperature polymers CITIBANK, N.A., AS COLLATERAL AGENT 2007-06-28 — — US disclosed
US-20070100088-A1 Flame resistant polymer blends GENERAL ELECTRIC COMPANY (US) 2007-05-03 — — US disclosed
US-20070066740-A1 Annular or tubular shaped articles of novel polymer blends CITIBANK, N.A., AS COLLATERAL AGENT 2007-03-22 — — US disclosed
US-20070066738-A1 Flame retardant polysulfone blends SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2007-03-22 — — US disclosed
US-20070065615-A1 ANNULAR OR TUBULAR SHAPED ARTICLES OF NOVEL POLYMER BLENDS CITIBANK, N.A., AS COLLATERAL AGENT 2007-03-22 — — US disclosed
US-20070066741-A1 High glass transition temperature thermoplastic articles CITIBANK, N.A., AS COLLATERAL AGENT 2007-03-22 — — US disclosed
US-20070066739-A1 Coated articles of manufacture made of high Tg polymer blends GENERAL ELECTRIC COMPANY 2007-03-22 — — US disclosed
US-20070066737-A1 Flame retardant polymer blends SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2007-03-22 — — US disclosed
US-7169859-B2 Weatherable, thermostable polymers having improved flow composition GENERAL ELECTRIC COMPANY (US) 2007-01-30 — — US disclosed
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