SCHEMBL260757

SCHEMBL260757

CC(C)(C)Oc1cccc(OC(=O)c2ccccc2)c1

nearest known ligand 0.55

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 4/20 0.55
▸ MAPT P10636 4/20 0.55
▸ L3MBTL1 Q9Y468 1/20 0.55
▸ KMT2A Q03164 8/20 0.55
▸ MEN1 O00255 1/20 0.54
▸ ESR1 P03372 2/20 0.51
▸ ESR2 Q92731 2/20 0.51
▸ ALDH1A1 P00352 3/20 0.49
▸ TSHR P16473 1/20 0.49
▸ HSD17B10 Q99714 1/20 0.49
▸ PKM P14618 1/20 0.47
▸ PARP10 Q53GL7 1/20 0.46
▸ NSD2 O96028 1/20 0.46
▸ PRSS1 P07477 1/20 0.46
▸ ACR P10323 1/20 0.46
▸ POLB P06746 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1785471 0.86 KMT2A (0.69) TDP1MAPTL3MBTL1KMT2AMEN1
SCHEMBL12808314 0.85 KMT2A (0.50) TDP1MAPTL3MBTL1KMT2AMEN1
SCHEMBL13894564 0.85 KMT2A (0.50) TDP1MAPTL3MBTL1KMT2AMEN1
SCHEMBL6674207 0.85 TDP1 (0.70) TDP1MAPTL3MBTL1KMT2AMEN1
SCHEMBL5705949 0.83 MAPT (0.63) TDP1MAPTL3MBTL1KMT2AMEN1
SCHEMBL14473537 0.83 KMT2A (0.48) TDP1MAPTL3MBTL1KMT2AMEN1
SCHEMBL13350221 0.83 KMT2A (0.48) TDP1MAPTL3MBTL1KMT2AMEN1
SCHEMBL411502 0.81 ESR1 (0.69) TDP1MAPTKMT2AMEN1ESR1
SCHEMBL8435530 0.81 MAPT (0.68) TDP1MAPTL3MBTL1KMT2AMEN1
SCHEMBL13110206 0.81 MAPT (0.69) TDP1MAPTL3MBTL1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8263691-B2 Release agent for transparent polyimide blends SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2012-09-11 — — US disclosed
US-20120052314-A1 MULTILAYER ARTICLES COMPRISING RESORCINOL ARYLATE POLYESTER AND METHOD FOR MAKING THEREOF SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2012-03-01 — — US disclosed
US-20120052314-A1 MULTILAYER ARTICLES COMPRISING RESORCINOL ARYLATE POLYESTER AND METHOD FOR MAKING THEREOF SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2012-03-01 — — US disclosed
US-8057903-B2 Injection molding; three-dimensional shape; using ionizing radiation SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2011-11-15 — — US disclosed
US-7932310-B2 Flame retardant polysulfone blends SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2011-04-26 — — US disclosed
US-7838602-B2 Weatherable, thermostable polymers having improved flow composition SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2010-11-23 — — US disclosed
US-7652107-B2 Blends of siloxane copolymers with polyaryl esters or polyaryl ester carbonates containing linkages derived from resorcinol, show improved flame resistance SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2010-01-26 — — US disclosed
US-20100009207-A1 FORMABLE THERMOPLASTIC MULTI-LAYER ARTICLE, A FORMED MULTI-LAYER ARTICLE, AN ARTICLE, AND A METHOD OF MAKING AN ARTICLE SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2010-01-14 — — US disclosed
US-7605221-B2 Aromatic polycarbonateester block or random copolymer and polysiloxane blend primarily containing isophthalic and terephthalic acids, resorcinol and dimethylsilanediol monomers; films are radiation transparent; improved ductility at lower temperatures; aircraft components SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2009-10-20 — — US disclosed
US-7557174-B2 Carboxy-terminated oligomeric polyester compositions and method for making SABIC INNOVATIVE PLASTICS IP BV (NL) 2009-07-07 — — US disclosed
US-20070100088-A1 Flame resistant polymer blends GENERAL ELECTRIC COMPANY (US) 2007-05-03 — — US disclosed
US-20070066740-A1 Annular or tubular shaped articles of novel polymer blends CITIBANK, N.A., AS COLLATERAL AGENT 2007-03-22 — — US disclosed
US-20070066738-A1 Flame retardant polysulfone blends SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2007-03-22 — — US disclosed
US-20070065615-A1 ANNULAR OR TUBULAR SHAPED ARTICLES OF NOVEL POLYMER BLENDS CITIBANK, N.A., AS COLLATERAL AGENT 2007-03-22 — — US disclosed
US-20070066737-A1 Flame retardant polymer blends SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2007-03-22 — — US disclosed
US-20070066739-A1 Coated articles of manufacture made of high Tg polymer blends GENERAL ELECTRIC COMPANY 2007-03-22 — — US disclosed
US-20070066741-A1 High glass transition temperature thermoplastic articles CITIBANK, N.A., AS COLLATERAL AGENT 2007-03-22 — — US disclosed
US-20070027271-A1 WEATHERABLE, THERMOSTABLE POLYMERS HAVING IMPROVED FLOW COMPOSITION GENERAL ELECTRIC COMPANY (US) 2007-02-01 — — US disclosed
US-20070027290-A1 Carboxy-terminated oligomeric polyester compositions and method for making SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2007-02-01 — — US disclosed
US-7169859-B2 Weatherable, thermostable polymers having improved flow composition GENERAL ELECTRIC COMPANY (US) 2007-01-30 — — US disclosed
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