Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | HPGD | P15428 | 4/20 | 0.60 |
| ▸ | NPC1 | O15118 | 3/20 | 0.60 |
| ▸ | RAB9A | P51151 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | TP53 | P04637 | 2/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.60 |
| ▸ | PKM | P14618 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.60 |
| ▸ | HPGDS | O60760 | 1/20 | 0.60 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.60 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13352093 | 0.96 | ALDH1A1 (0.60) | ALDH1A1MEN1KMT2AHPGDNPC1 | |
| SCHEMBL14319164 | 0.92 | MEN1 (0.58) | ALDH1A1MEN1KMT2AHPGDNPC1 | |
| SCHEMBL13352244 | 0.91 | MEN1 (0.71) | ALDH1A1MEN1KMT2AHPGDNPC1 | |
| SCHEMBL13352097 | 0.91 | MEN1 (0.57) | ALDH1A1MEN1KMT2AHPGDNPC1 | |
| SCHEMBL9607108 | 0.89 | CNR2 (0.58) | ALDH1A1MEN1KMT2AHPGDNPC1 | |
| SCHEMBL14021036 | 0.88 | MEN1 (0.54) | ALDH1A1MEN1KMT2AHPGDNPC1 | |
| SCHEMBL13352143 | 0.88 | PKM (0.57) | ALDH1A1MEN1KMT2AHPGDNPC1 | |
| SCHEMBL14021144 | 0.87 | SMN1; SMN2 (0.55) | ALDH1A1MEN1KMT2AHPGDNPC1 | |
| SCHEMBL14021155 | 0.87 | BCHE (0.59) | ALDH1A1MEN1KMT2AHPGDNPC1 | |
| SCHEMBL14021147 | 0.86 | MEN1 (0.52) | ALDH1A1MEN1KMT2AHPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100130497-A1 | Therapeutic Compounds | FIBROTECH THERAPEUTICS PTY LTD (AU) | 2010-05-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100130497-A1 | Therapeutic Compounds | NFATC1, NAT1, AADAC | ALDH1A1 199/4885MEN1 2640/4885KMT2A 1798/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.