Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 3/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16194436 | 0.84 | CYP1A2 (0.44) | CYP2A6CYP1A2RAB9ANPC1TDP1 | |
| SCHEMBL27937848 | 0.79 | CYP1A2 (0.41) | CYP2A6CYP1A2RAB9ANPC1TDP1 | |
| SCHEMBL20248915 | 0.79 | CYP2A6 (0.52) | CYP2A6CYP1A2RAB9ANPC1TDP1 | |
| SCHEMBL16194439 | 0.78 | ALDH1A1 (0.53) | CYP2A6CYP1A2TDP1KMT2AMEN1 | |
| SCHEMBL27937793 | 0.78 | CYP1A2 (0.39) | CYP2A6CYP1A2RAB9ANPC1TDP1 | |
| SCHEMBL16194432 | 0.78 | CYP1A2 (0.59) | CYP2A6CYP1A2RAB9ANPC1TDP1 | |
| SCHEMBL19422040 | 0.78 | NQO2 (0.55) | CYP2A6CYP1A2KMT2AMEN1IDO1 | |
| SCHEMBL27937956 | 0.78 | FADS1 (0.43) | CYP2A6CYP1A2KMT2AMEN1IDO1 | |
| SCHEMBL27919141 | 0.76 | HTR6 (0.42) | CYP2A6CYP1A2TDP1KMT2AMEN1 | |
| SCHEMBL15214817 | 0.76 | CYP1A2 (0.48) | CYP2A6CYP1A2IDO1ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12083498-B2 | Chromatographic materials for the separation of unsaturated molecules | WATERS TECHNOLOGIES CORPORATION (US) | 2024-09-10 | — | — | US | disclosed |
| CN-111644164-B | Chromatographic material for separating unsaturated molecules | 沃特世科技公司 | 2024-03-08 | — | — | CN | disclosed |
| US-20210023531-A1 | CHROMATOGRAPHIC MATERIALS FOR THE SEPARATION OF UNSATURATED MOLECULES | WATERS TECHNOLOGIES CORPORATION (US) | 2021-01-28 | — | — | US | disclosed |
| CN-111644164-A | Chromatographic materials for separating unsaturated molecules | 沃特世科技公司 | 2020-09-11 | — | — | CN | disclosed |
| US-10744484-B2 | Chromatographic materials for the separation of unsaturated molecules | WATERS TECHNOLOGIES CORPORATION (US) | 2020-08-18 | — | — | US | disclosed |
| CN-106457066-B | Chromatographic materials for separating unsaturated molecules | 沃特世科技公司 | 2020-08-14 | — | — | CN | disclosed |
| US-20180345248-A1 | CHROMATOGRAPHIC MATERIALS FOR THE SEPARATION OF UNSATURATED MOLECULES | WATERS TECHNOLOGIES CORPORATION (US) | 2018-12-06 | — | — | US | disclosed |
| US-10092894-B2 | Chromatographic materials for the separation of unsaturated molecules | WATERS TECHNOLOGIES CORPORATION (US) | 2018-10-09 | — | — | US | disclosed |
| EP-3113857-A1 | CHROMATOGRAPHIC MATERIALS FOR THE SEPARATION OF UNSATURATED MOLECULES | Waters Technologies Corporation (US) | 2017-01-11 | — | — | EP | disclosed |
| WO-2015134317-A9 | CHROMATOGRAPHIC MATERIALS FOR THE SEPARATION OF UNSATURATED MOLECULES | WATERS TECHNOLOGIES CORPORATION (US) | 2016-08-04 | — | — | WO | disclosed |
| WO-2015134317-A1 | CHROMOTOGRAPHIC MATERIALS FOR THE SEPARATION OF UNSATURATED MOLECULES | WATERS TECHNOLOGIES CORPORATION (US) | 2015-09-11 | — | — | WO | disclosed |
| US-20140319057-A1 | CHROMATOGRAPHIC MATERIALS FOR THE SEPARATION OF UNSATURATED MOLECULES | WATERS TECHNOLOGIES CORPORATION (US) | 2014-10-30 | — | — | US | disclosed |
| EP-2121572-A2 | PREPARATION AND UTILITY OF SUBSTITUTED ALLYLAMINES | Auspex Pharmaceuticals Inc. (US) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008073863-A2 | PREPARATION AND UTILITY OF SUBSTITUTED ALLYLAMINES | AUSPEX PHARMACEUTICALS, INC. (US) | 2008-06-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10092894-B2 | Chromatographic materials for the separation of unsaturated molecules | AHR, NR1H3, ARNT | CYP2A6 460/4885CYP1A2 669/4885RAB9A 4527/4885 |
| US-20210023531-A1 | CHROMATOGRAPHIC MATERIALS FOR THE SEPARATION OF UNSATURATED MOLECULES | C9, EPHX2, ALOX5 | CYP2A6 539/4885CYP1A2 719/4885RAB9A 4506/4885 |
| US-10744484-B2 | Chromatographic materials for the separation of unsaturated molecules | C9, EPHX2, ALOX5 | CYP2A6 539/4885CYP1A2 719/4885RAB9A 4506/4885 |
| US-12083498-B2 | Chromatographic materials for the separation of unsaturated molecules | C9, EPHX2, ALOX5 | CYP2A6 539/4885CYP1A2 719/4885RAB9A 4506/4885 |
| US-20180345248-A1 | CHROMATOGRAPHIC MATERIALS FOR THE SEPARATION OF UNSATURATED MOLECULES | AHR, NR1H3, ARNT | CYP2A6 460/4885CYP1A2 669/4885RAB9A 4527/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.