Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | PKLR | P30613 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.45 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12621923 | 0.88 | L3MBTL1 (0.78) | L3MBTL1ALDH1A1NPC1PKMPKLR | |
| SCHEMBL12623925 | 0.88 | L3MBTL1 (0.67) | L3MBTL1ALDH1A1NPC1PKMPKLR | |
| SCHEMBL18133264 | 0.86 | L3MBTL1 (0.66) | L3MBTL1ALDH1A1NPC1PKMPKLR | |
| SCHEMBL12623987 | 0.85 | L3MBTL1 (0.65) | L3MBTL1ALDH1A1NPC1PKMPKLR | |
| SCHEMBL12623954 | 0.84 | L3MBTL1 (0.64) | L3MBTL1ALDH1A1NPC1PKMPKLR | |
| SCHEMBL12623952 | 0.84 | L3MBTL1 (0.63) | L3MBTL1ALDH1A1NPC1PKMPKLR | |
| SCHEMBL12623944 | 0.83 | L3MBTL1 (0.59) | L3MBTL1ALDH1A1NPC1PKMPKLR | |
| SCHEMBL12626207 | 0.82 | L3MBTL1 (0.61) | L3MBTL1ALDH1A1 | |
| SCHEMBL12655726 | 0.81 | L3MBTL1 (0.60) | L3MBTL1ALDH1A1KDM4EHCRTR1HCRTR2 | |
| SCHEMBL23159676 | 0.81 | L3MBTL1 (0.60) | L3MBTL1ALDH1A1NPC1PKMPKLR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010051476-A1 | FILAMIN A-BINDING ANTI-INFLAMMATORY ANALGESIC | PAIN THERAPEUTICS, INC. (US) | 2010-05-06 | — | — | WO | disclosed |