Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GGPS1 | O95749 | 3/20 | 0.38 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.37 |
| ▸ | ANPEP | P15144 | 1/20 | 0.34 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | ADH1B | P00325 | 1/20 | 0.32 |
| ▸ | ADH1C | P00326 | 1/20 | 0.32 |
| ▸ | ADH1A | P07327 | 1/20 | 0.32 |
| ▸ | ADH4 | P08319 | 1/20 | 0.32 |
| ▸ | ADH7 | P40394 | 1/20 | 0.32 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.32 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13354589 | 0.91 | GGPS1 (0.35) | GGPS1SPHK1ANPEPERAP2LMNA | |
| SCHEMBL12977302 | 0.91 | GGPS1 (0.35) | GGPS1SPHK1ANPEPERAP2LMNA | |
| SCHEMBL12977313 | 0.91 | GGPS1 (0.35) | GGPS1SPHK1ANPEPERAP2LMNA | |
| SCHEMBL12977305 | 0.85 | EPHX1 (0.41) | GGPS1SPHK1LMNACYP2D6PLA2G1B | |
| SCHEMBL12977314 | 0.85 | EPHX1 (0.41) | GGPS1SPHK1LMNACYP2D6PLA2G1B | |
| SCHEMBL16500373 | 0.82 | SPHK1 (0.36) | GGPS1SPHK1GPR84FFAR1 | |
| SCHEMBL16919615 | 0.82 | SPHK1 (0.36) | GGPS1SPHK1ANPEPERAP2LMNA | |
| SCHEMBL13354385 | 0.81 | SPHK1 (0.41) | GGPS1SPHK1ANPEPERAP2LMNA | |
| SCHEMBL12976837 | 0.81 | SPHK1 (0.35) | GGPS1SPHK1ANPEPERAP2LMNA | |
| SCHEMBL13354587 | 0.79 | EPHX1 (0.44) | SPHK1ANPEPERAP2LMNACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010053572-A2 | AMINOALCOHOL LIPIDOIDS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2010-05-14 | — | — | WO | disclosed |