Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GGPS1 | O95749 | 3/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.34 |
| ▸ | ANPEP | P15144 | 1/20 | 0.32 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13354518 | 0.91 | GGPS1 (0.38) | GGPS1SPHK1ANPEPERAP2LMNA | |
| SCHEMBL12977313 | 0.90 | GGPS1 (0.35) | GGPS1SPHK1ANPEPERAP2LMNA | |
| SCHEMBL12977302 | 0.90 | GGPS1 (0.35) | GGPS1SPHK1ANPEPERAP2LMNA | |
| SCHEMBL12976837 | 0.85 | SPHK1 (0.35) | GGPS1SPHK1ANPEPERAP2LMNA | |
| SCHEMBL12977339 | 0.81 | SPHK1 (0.36) | SPHK1ANPEPERAP2LMNA | |
| SCHEMBL16500373 | 0.81 | SPHK1 (0.36) | GGPS1SPHK1 | |
| SCHEMBL12977360 | 0.81 | SPHK1 (0.32) | SPHK1 | |
| SCHEMBL19148736 | 0.80 | PKM (0.32) | LMNA | |
| SCHEMBL13008057 | 0.80 | PKM (0.33) | GGPS1 | |
| SCHEMBL16919607 | 0.79 | L3MBTL1 (0.32) | SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010053572-A2 | AMINOALCOHOL LIPIDOIDS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2010-05-14 | — | — | WO | disclosed |