Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.30 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17549734 | 1.00 | LMNA (0.32) | LMNACES2LPAR1LPAR3 | |
| SCHEMBL2483152 | 1.00 | LMNA (0.32) | LMNACES2LPAR1LPAR3 | |
| SCHEMBL17549723 | 1.00 | LMNA (0.32) | LMNACES2LPAR1LPAR3 | |
| SCHEMBL1703747 | 1.00 | LMNA (0.32) | LMNACES2LPAR1LPAR3 | |
| SCHEMBL1703745 | 1.00 | LMNA (0.32) | LMNACES2LPAR1LPAR3 | |
| SCHEMBL6513513 | 0.97 | CES2 (0.31) | LMNACES2LPAR1LPAR3 | |
| SCHEMBL6291255 | 0.93 | CES2 (0.38) | LMNACES2LPAR1LPAR3 | |
| SCHEMBL13826951 | 0.93 | CES2 (0.38) | LMNACES2LPAR1LPAR3 | |
| SCHEMBL11882704 | 0.93 | CES2 (0.38) | LMNACES2LPAR1LPAR3 | |
| SCHEMBL17691447 | 0.93 | CES2 (0.38) | LMNACES2LPAR1LPAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010053572-A2 | AMINOALCOHOL LIPIDOIDS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2010-05-14 | — | — | WO | disclosed |