Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | LPAR1 | Q92633 | 5/20 | 0.44 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.44 |
| ▸ | MLYCD | O95822 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.36 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.36 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.35 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ABCB4 | P21439 | 1/20 | 0.35 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.35 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.35 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13355362 | 0.77 | CXCR4 (0.59) | MAPTKDM4E | |
| SCHEMBL2408859 | 0.74 | HDAC1 (0.56) | MAPTKDM4ELPAR1LPAR3MLYCD | |
| SCHEMBL4035675 | 0.72 | MAPT (0.67) | MAPTKDM4ELPAR1LPAR3HDAC3 | |
| SCHEMBL5995 | 0.69 | LPAR1 (0.61) | MAPTKDM4ELPAR1LPAR3MLYCD | |
| SCHEMBL5529169 | 0.68 | MAPT (0.62) | MAPTKDM4ELPAR1LPAR3LPAR2 | |
| SCHEMBL7061 | 0.68 | MAPT (0.53) | MAPTKDM4ELPAR1LPAR3LPAR2 | |
| SCHEMBL7036 | 0.66 | LPAR1 (0.52) | MAPTKDM4ELPAR1LPAR3MLYCD | |
| SCHEMBL6795 | 0.65 | KDM4E (0.50) | MAPTKDM4ELPAR1LPAR3LPAR2 | |
| SCHEMBL25401241 | 0.65 | MAPT (0.57) | MAPTKDM4ELPAR1LPAR3LPAR2 | |
| SCHEMBL4200801 | 0.65 | KDM4E (0.58) | MAPTKDM4ELPAR1LPAR3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010057101-A2 | COMPOUNDS USEFUL AS HIV BLOCKERS | SCHERING CORPORATION (US) | 2010-05-20 | — | — | WO | disclosed |