Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 7/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.50 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.45 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2413988 | 0.84 | HDAC1 (0.56) | HDAC1HDAC2MAPTHDAC6HDAC8 | |
| SCHEMBL2408856 | 0.78 | LPAR1 (0.53) | HDAC1HDAC2MAPTKDM4EHDAC6 | |
| SCHEMBL5995 | 0.77 | LPAR1 (0.61) | MAPTKDM4ELPAR1LPAR3SMN1; SMN2 | |
| SCHEMBL2407920 | 0.74 | HDAC8 (0.82) | HDAC1HDAC2HDAC6HDAC8NPC1 | |
| SCHEMBL13355167 | 0.74 | MAPT (0.49) | HDAC1HDAC2MAPTKDM4EHDAC6 | |
| SCHEMBL7061 | 0.73 | MAPT (0.53) | MAPTKDM4ELPAR1LPAR3SMN1; SMN2 | |
| SCHEMBL7036 | 0.73 | LPAR1 (0.52) | MAPTKDM4ELPAR1LPAR3MEN1 | |
| SCHEMBL4035675 | 0.73 | MAPT (0.67) | HDAC1HDAC2MAPTKDM4EHDAC6 | |
| SCHEMBL2410550 | 0.72 | KMT2A (0.67) | HDAC2MAPTHDAC6HDAC8SMN1; SMN2 | |
| SCHEMBL2414872 | 0.72 | HDAC1 (0.62) | HDAC1HDAC2HDAC6HDAC8NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011106632-A1 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2011-09-01 | — | — | WO | disclosed |