Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12297443 | 0.68 | KMT2A (0.64) | KDM4EMEN1ALDH1A1GAAMAPT | |
| SCHEMBL12297426 | 0.67 | KMT2A (0.76) | KDM4EMEN1ALDH1A1GAAMAPT | |
| SCHEMBL12297404 | 0.66 | KMT2A (1.00) | KDM4EMEN1ALDH1A1GAAMAPT | |
| SCHEMBL19918060 | 0.65 | KMT2A (0.75) | KDM4EMEN1ALDH1A1GAAMAPT | |
| SCHEMBL12297457 | 0.63 | KMT2A (0.57) | KDM4EMEN1ALDH1A1GAAMAPT | |
| SCHEMBL5975794 | 0.60 | KDM4E (0.47) | KDM4EMEN1ALDH1A1GAAMAPT | |
| SCHEMBL12297482 | 0.60 | SOD1 (0.55) | KDM4EMEN1ALDH1A1GAAMAPT | |
| SCHEMBL23401931 | 0.59 | MEN1 (0.46) | KDM4EMEN1ALDH1A1GAAMAPT | |
| SCHEMBL12297385 | 0.58 | SOD1 (0.54) | KDM4EMEN1ALDH1A1GAAMAPT | |
| SCHEMBL23402985 | 0.58 | DAO (0.46) | KDM4EMEN1ALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010059241-A2 | TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS | CAMBRIA PHARMACEUTICALS, INC. (US) | 2010-05-27 | — | — | WO | disclosed |