Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.74 |
| ▸ | MEN1 | O00255 | 1/20 | 0.74 |
| ▸ | HTT | P42858 | 1/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.74 |
| ▸ | LMNA | P02545 | 2/20 | 0.73 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.73 |
| ▸ | AVPR1A | P37288 | 10/20 | 0.70 |
| ▸ | AVPR2 | P30518 | 8/20 | 0.70 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3455465 | 0.89 | ALDH1A1 (0.74) | ALDH1A1MEN1HTTKMT2ALMNA | |
| SCHEMBL2895100 | 0.88 | ALDH1A1 (0.73) | ALDH1A1MEN1HTTKMT2ALMNA | |
| SCHEMBL2895098 | 0.88 | ALDH1A1 (0.73) | ALDH1A1MEN1HTTKMT2ALMNA | |
| SCHEMBL3456179 | 0.88 | ALDH1A1 (0.73) | ALDH1A1MEN1HTTKMT2ALMNA | |
| SCHEMBL3455687 | 0.87 | LMNA (0.74) | ALDH1A1MEN1HTTKMT2ALMNA | |
| SCHEMBL2895086 | 0.85 | ALDH1A1 (0.70) | ALDH1A1MEN1HTTKMT2ALMNA | |
| SCHEMBL3455328 | 0.85 | ALDH1A1 (0.70) | ALDH1A1MEN1HTTKMT2ALMNA | |
| SCHEMBL13355138 | 0.85 | ALDH1A1 (1.00) | ALDH1A1MEN1HTTKMT2ALMNA | |
| SCHEMBL3818092 | 0.85 | ALDH1A1 (0.70) | ALDH1A1MEN1HTTKMT2ALMNA | |
| SCHEMBL3455628 | 0.85 | ALDH1A1 (0.69) | ALDH1A1MEN1HTTKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1787982-B1 | 11Beta-Hydroxysteroid dehydrogenase type 1 active compounds | HIGH POINT PHARMACEUTICALS LLC (US) | 2010-05-12 | — | — | EP | disclosed |