Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 19/20 | 0.51 |
| ▸ | HTR2A | P28223 | 17/20 | 0.51 |
| ▸ | HTR2B | P41595 | 17/20 | 0.51 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11834071 | 0.85 | HTR2C (0.42) | HTR2CHTR2AHTR2BCHRNB2CHRNA4 | |
| SCHEMBL29400162 | 0.85 | HTR2C (0.42) | HTR2CHTR2AHTR2BCHRNB2CHRNA4 | |
| SCHEMBL10154861 | 0.83 | HTR2C (0.40) | HTR2CHTR2AHTR2BCHRNB2CHRNA4 | |
| SCHEMBL10154858 | 0.83 | HTR2C (0.40) | HTR2CHTR2AHTR2BCHRNB2CHRNA4 | |
| SCHEMBL14300108 | 0.83 | HTR2C (0.40) | HTR2CHTR2AHTR2BCHRNB2CHRNA4 | |
| SCHEMBL18560193 | 0.80 | CHRNB2 (0.42) | HTR2CHTR2AHTR2BCHRNB2CHRNA4 | |
| SCHEMBL12882685 | 0.79 | HTR2C (0.47) | HTR2CHTR2AHTR2BCHRNB2CHRNA4 | |
| SCHEMBL18560180 | 0.79 | KIF11 (0.40) | HTR2CCHRNB2CHRNA4 | |
| SCHEMBL18560189 | 0.79 | KIF11 (0.40) | HTR2CCHRNB2CHRNA4 | |
| SCHEMBL12882862 | 0.76 | HTR2A (0.45) | HTR2CHTR2AHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2184064-A2 | LIGANDS OF 5-HT6 RECEPTORS, A PHARMACEUTICAL COMPOSITION, METHOD FOR THE PRODUCTION AND USE THEREOF | Alla Chem, LLC. (US) | 2010-05-12 | — | — | EP | disclosed |
| WO-2008060190-A2 | LIGANDS OF 5-HT6 RECEPTORS, A PHARMACEUTICAL COMPOSITION, METHOD FOR THE PRODUCTION AND USE THEREOF | ALLA CHEM, LLC (US) | 2008-05-22 | — | — | WO | disclosed |