Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8035192 | 0.90 | HRH3 (0.35) | KDM4EALDH1A1MAPTSMN1; SMN2GAA | |
| SCHEMBL14216399 | 0.90 | HRH3 (0.35) | KDM4EALDH1A1MAPTSMN1; SMN2GAA | |
| SCHEMBL13356207 | 0.89 | ALDH1A1 (0.50) | KDM4EALDH1A1MAPTSMN1; SMN2GAA | |
| SCHEMBL13356274 | 0.89 | ALDH1A1 (0.50) | KDM4EALDH1A1MAPTSMN1; SMN2GAA | |
| SCHEMBL13862077 | 0.89 | ALDH1A1 (0.50) | KDM4EALDH1A1MAPTSMN1; SMN2GAA | |
| SCHEMBL13356272 | 0.88 | ALDH1A1 (0.39) | KDM4EALDH1A1MAPTSMN1; SMN2GAA | |
| SCHEMBL8038336 | 0.88 | ALDH1A1 (0.39) | KDM4EALDH1A1MAPTSMN1; SMN2GAA | |
| SCHEMBL13356265 | 0.84 | SMN1; SMN2 (0.41) | KDM4EALDH1A1MAPTSMN1; SMN2GAA | |
| SCHEMBL13356270 | 0.83 | ALDH1A1 (0.36) | KDM4EALDH1A1MAPTSMN1; SMN2GAA | |
| SCHEMBL14216279 | 0.81 | HRH3 (0.39) | KDM4EALDH1A1MAPTSMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2184064-A2 | LIGANDS OF 5-HT6 RECEPTORS, A PHARMACEUTICAL COMPOSITION, METHOD FOR THE PRODUCTION AND USE THEREOF | Alla Chem, LLC. (US) | 2010-05-12 | — | — | EP | disclosed |
| WO-2008060190-A2 | LIGANDS OF 5-HT6 RECEPTORS, A PHARMACEUTICAL COMPOSITION, METHOD FOR THE PRODUCTION AND USE THEREOF | ALLA CHEM, LLC (US) | 2008-05-22 | — | — | WO | disclosed |