Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | APOBEC3A | P31941 | 2/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 2/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | RXRG | P48443 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13862077 | 0.88 | ALDH1A1 (0.50) | SMN1; SMN2ALDH1A1MAPTKDM4EGAA | |
| SCHEMBL13356207 | 0.88 | ALDH1A1 (0.50) | SMN1; SMN2ALDH1A1MAPTKDM4EGAA | |
| SCHEMBL13356274 | 0.88 | ALDH1A1 (0.50) | SMN1; SMN2ALDH1A1MAPTKDM4EGAA | |
| SCHEMBL13356232 | 0.84 | KDM4E (0.40) | SMN1; SMN2ALDH1A1MAPTKDM4EGAA | |
| SCHEMBL13356267 | 0.82 | GAA (0.41) | SMN1; SMN2ALDH1A1MAPTKDM4EGAA | |
| SCHEMBL10128038 | 0.79 | HDAC6 (0.54) | SMN1; SMN2ALDH1A1MAPTKDM4EGAA | |
| SCHEMBL8034703 | 0.79 | HDAC6 (0.54) | SMN1; SMN2ALDH1A1MAPTKDM4EGAA | |
| SCHEMBL8038336 | 0.79 | ALDH1A1 (0.39) | SMN1; SMN2ALDH1A1MAPTKDM4EGAA | |
| SCHEMBL13356272 | 0.79 | ALDH1A1 (0.39) | SMN1; SMN2ALDH1A1MAPTKDM4EGAA | |
| SCHEMBL13356268 | 0.78 | ALDH1A1 (0.42) | SMN1; SMN2ALDH1A1MAPTKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2184064-A2 | LIGANDS OF 5-HT6 RECEPTORS, A PHARMACEUTICAL COMPOSITION, METHOD FOR THE PRODUCTION AND USE THEREOF | Alla Chem, LLC. (US) | 2010-05-12 | — | — | EP | disclosed |