Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 5/20 | 0.45 |
| ▸ | HTR2C | P28335 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.43 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.43 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.41 |
| ▸ | RPS6KB1 | P23443 | 4/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | AKT2 | P31751 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2390103 | 0.84 | STAT3 (0.47) | STAT3HTR2AHTR2CKDM4ECYP1A2 | |
| SCHEMBL3832693 | 0.75 | MAPT (0.43) | KDM4ERPS6KB1 | |
| SCHEMBL24735180 | 0.74 | MAPT (0.38) | KDM4E | |
| SCHEMBL10621170 | 0.74 | HTR2A (0.56) | STAT3HTR2AHTR2CKDM4ECYP1A2 | |
| SCHEMBL27404764 | 0.73 | LMNA (0.55) | STAT3KDM4EDGAT1 | |
| SCHEMBL30890323 | 0.73 | LMNA (0.55) | STAT3KDM4EDGAT1 | |
| SCHEMBL13356261 | 0.72 | KMT2A (0.57) | KDM4ETSHR | |
| SCHEMBL20231575 | 0.72 | MAPT (0.57) | KDM4ETSHR | |
| SCHEMBL30612346 | 0.72 | PDE10A (0.48) | KDM4E | |
| SCHEMBL24735175 | 0.72 | PDE10A (0.48) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010059602-A2 | INHIBITORS OF DIACYLGLYCEROL ACYLTRANSFERASE | SCHERING CORPORATION (US) | 2010-05-27 | — | — | WO | disclosed |