Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 10/20 | 0.45 |
| ▸ | MAOA | P21397 | 9/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2924632 | 0.85 | MAOB (0.40) | MAOBMAOAKMT2AEPHX2NPC1 | |
| SCHEMBL13356496 | 0.85 | MAOB (0.39) | MAOBMAOAKMT2AEPHX2NPC1 | |
| SCHEMBL19629987 | 0.80 | MAOB (0.39) | MAOBMAOAKMT2AEPHX2NPC1 | |
| SCHEMBL10285185 | 0.80 | EPHX2 (0.50) | MAOBMAOAKMT2AEPHX2NPC1 | |
| SCHEMBL2797763 | 0.77 | MAOB (0.40) | MAOBMAOAKMT2AEPHX2NPC1 | |
| SCHEMBL2123339 | 0.76 | MAOA (0.41) | MAOBMAOAKMT2AEPHX2NPC1 | |
| SCHEMBL26386762 | 0.76 | MAOB (0.39) | MAOBMAOAKMT2AEPHX2NPC1 | |
| SCHEMBL25110146 | 0.76 | KMT2A (0.43) | MAOBMAOAKMT2AEPHX2NPC1 | |
| SCHEMBL21400792 | 0.76 | EPHX2 (0.40) | MAOBMAOAKMT2AEPHX2NPC1 | |
| SCHEMBL2926434 | 0.74 | ALDH1A1 (0.60) | MAOBMAOAKMT2AEPHX2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2181996-A1 | Aminopiperidine derivatives | GLAXO GROUP LIMITED (GB) | 2010-05-05 | — | — | EP | disclosed |