Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 10/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 8/20 | 0.43 |
| ▸ | TUBB | P07437 | 8/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 8/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 8/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 8/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 8/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 8/20 | 0.43 |
| ▸ | TUBB2A | Q13885 | 8/20 | 0.43 |
| ▸ | TUBB8 | Q3ZCM7 | 8/20 | 0.43 |
| ▸ | TUBA3E | Q6PEY2 | 8/20 | 0.43 |
| ▸ | TUBA1A | Q71U36 | 8/20 | 0.43 |
| ▸ | TUBA1C | Q9BQE3 | 8/20 | 0.43 |
| ▸ | TUBB6 | Q9BUF5 | 8/20 | 0.43 |
| ▸ | TUBB2B | Q9BVA1 | 8/20 | 0.43 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12130399 | 0.89 | TUBB4A (0.40) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL1336799 | 0.84 | TUBB1 (0.44) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL12132026 | 0.81 | TUBB4A (0.43) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL1337332 | 0.79 | TUBB1 (0.50) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL1337868 | 0.79 | TUBB4A (0.47) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL12132029 | 0.79 | TUBB1 (0.47) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL1337548 | 0.78 | TUBB4A (0.46) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL1337461 | 0.78 | TUBB4A (0.51) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL1335915 | 0.78 | TUBB1 (0.47) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL13931880 | 0.76 | TUBB1 (0.49) | TUBB1TUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110275643-A1 | AROYLQUINOLINE COMPOUNDS | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2011-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110275643-A1 | AROYLQUINOLINE COMPOUNDS | TUBA1C, TUBB1, TUBB3 | TUBB1 2/4885TUBB4A 11/4885TUBB 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.