Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 18/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2181557 | 0.85 | SLC6A9 (0.45) | SLC6A9KCNH2GPR119 | |
| SCHEMBL2184142 | 0.84 | SLC6A9 (0.49) | SLC6A9KCNH2GPR119 | |
| SCHEMBL2184722 | 0.82 | SLC6A9 (0.54) | SLC6A9GPR119 | |
| SCHEMBL2183244 | 0.81 | GPR119 (0.59) | GPR119 | |
| SCHEMBL2183152 | 0.81 | GPR119 (0.59) | KCNH2GPR119 | |
| SCHEMBL2184347 | 0.81 | GPR119 (0.48) | SLC6A9KCNH2AOC3GPR119 | |
| SCHEMBL2182314 | 0.81 | GPR119 (0.49) | SLC6A9GPR119 | |
| SCHEMBL2181751 | 0.80 | GPR119 (0.49) | SLC6A9KCNH2AOC3GPR119 | |
| SCHEMBL2181458 | 0.78 | SLC6A9 (0.41) | SLC6A9KCNH2GPR119 | |
| SCHEMBL2183518 | 0.78 | KDM4E (0.45) | SLC6A9KCNH2AOC3GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8293729-B2 | Compounds, pharmaceutical composition and methods relating thereto | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-10-23 | — | — | US | disclosed |