Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.57 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13324897 | 1.00 | PPARG (0.57) | PPARGSLC22A12ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL13359395 | 0.93 | PPARG (0.62) | PPARGSLC22A12HTTMEN1KMT2A | |
| SCHEMBL13324898 | 0.93 | PPARG (0.62) | PPARGSLC22A12HTTMEN1KMT2A | |
| SCHEMBL3299123 | 0.92 | PPARG (0.60) | PPARGSLC22A12HPGDSMN1; SMN2HTT | |
| SCHEMBL12189840 | 0.92 | PPARG (0.60) | PPARGSLC22A12HPGDSMN1; SMN2HTT | |
| SCHEMBL3299728 | 0.92 | PPARG (0.60) | PPARGSLC22A12HPGDSMN1; SMN2HTT | |
| SCHEMBL3299127 | 0.92 | PPARG (0.60) | PPARGSLC22A12HPGDSMN1; SMN2HTT | |
| SCHEMBL16502054 | 0.89 | PPARG (0.57) | PPARGSLC22A12HTTMEN1KMT2A | |
| SCHEMBL13374097 | 0.84 | PPARG (0.58) | PPARGSLC22A12ALDH1A1HPGDGAA | |
| SCHEMBL14547394 | 0.84 | ALDH1A1 (0.44) | PPARGSLC22A12ALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1940387-B1 | PROCESS FOR THE STEREOSELECTIVE PREPARATION OF (-)-HALOFENATE AND INTERMEDIATES THEREOF | METABOLEX INC (US) | 2012-11-28 | — | — | EP | disclosed |
| US-7714131-B2 | Process for the stereoselective preparation of (−)-halofenate and derivatives thereof | METABOLEX, INC. (US) | 2010-05-11 | — | — | US | disclosed |
| WO-2007038243-A1 | PROCESS FOR THE STEREOSELECTIVE PREPARATION OF (-)-HALOFENATE AND INTERMEDIATES THEREOF | METABOLEX, INC. (US) | 2007-04-05 | — | — | WO | disclosed |
| US-20070072858-A1 | Process for the stereoselective preparation of (-)-halofenate and derivatives thereof | METABOLEX, INC. (US) | 2007-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070072858-A1 | Process for the stereoselective preparation of (-)-halofenate and derivatives thereof | CCNY, C1S, CBR3 | PPARG 1448/4885SLC22A12 2018/4885ALDH1A1 3229/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.