Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.60 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | MC4R | P32245 | 2/20 | 0.39 |
| ▸ | KLRK1 | P26718 | 1/20 | 0.38 |
| ▸ | MICA | Q29983 | 1/20 | 0.38 |
| ▸ | RAET1L | Q5VY80 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12189840 | 1.00 | PPARG (0.60) | PPARGSLC22A12LMNAHTTMAPT | |
| SCHEMBL3299127 | 1.00 | PPARG (0.60) | PPARGSLC22A12LMNAHTTMAPT | |
| SCHEMBL3299728 | 1.00 | PPARG (0.60) | PPARGSLC22A12LMNAHTTMAPT | |
| SCHEMBL13359395 | 0.96 | PPARG (0.62) | PPARGSLC22A12LMNAHTTMAPT | |
| SCHEMBL13324898 | 0.96 | PPARG (0.62) | PPARGSLC22A12LMNAHTTMAPT | |
| SCHEMBL13324897 | 0.92 | PPARG (0.57) | PPARGSLC22A12LMNAHTTMAPT | |
| SCHEMBL16502054 | 0.92 | PPARG (0.57) | PPARGSLC22A12LMNAHTTMAPT | |
| SCHEMBL13359396 | 0.92 | PPARG (0.57) | PPARGSLC22A12LMNAHTTMAPT | |
| SCHEMBL14547522 | 0.91 | PPARG (0.61) | PPARGSLC22A12LMNAHTTMAPT | |
| SCHEMBL13359397 | 0.91 | PPARG (0.61) | PPARGSLC22A12LMNAHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160075636-A1 | Process for the Preparation of (-)-(4-Chloro-Phenyl)-(3-Trifluoromethyl-Phenoxy)-Acetic Acid 2-Acetylamino-Ethyl Ester | CYMABAY THERAPEUTICS, INC. (US) | 2016-03-17 | — | — | US | disclosed |
| US-8541614-B2 | Process for the preparation of (−)-(4-chloro-phenyl)-(3-trifluoromethyl-phenoxy)-acetic acid 2-acetylamino-ethyl ester | METABOLEX, INC. (US) | 2013-09-24 | — | — | US | disclosed |
| US-7714131-B2 | Process for the stereoselective preparation of (−)-halofenate and derivatives thereof | METABOLEX, INC. (US) | 2010-05-11 | — | — | US | disclosed |
| US-20100093854-A1 | PROCESS FOR THE PREPARATION OF (-)-(4-CHLORO-PHENYL)-(3-TRIFLUOROMETHYL-PHENOXY)-ACETIC ACID 2-ACETYLAMINO-ETHYL ESTER | DIATEX, INC. | 2010-04-15 | — | — | US | disclosed |
| US-20070072858-A1 | Process for the stereoselective preparation of (-)-halofenate and derivatives thereof | METABOLEX, INC. (US) | 2007-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160075636-A1 | Process for the Preparation of (-)-(4-Chloro-Phenyl)-(3-Trifluoromethyl-Phenoxy)-Acetic Acid 2-Acetylamino-Ethyl Ester | PC, ACACA, ACACB | PPARG 136/4885SLC22A12 2169/4885LMNA 2514/4885 |
| US-20070072858-A1 | Process for the stereoselective preparation of (-)-halofenate and derivatives thereof | CCNY, C1S, CBR3 | PPARG 1448/4885SLC22A12 2018/4885LMNA 817/4885 |
| US-20100093854-A1 | PROCESS FOR THE PREPARATION OF (-)-(4-CHLORO-PHENYL)-(3-TRIFLUOROMETHYL-PHENOXY)-ACETIC ACID 2-ACETYLAMINO-ETHYL ESTER | PC, ACACA, ACACB | PPARG 136/4885SLC22A12 2169/4885LMNA 2514/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.