Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.61 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KLRK1 | P26718 | 1/20 | 0.39 |
| ▸ | MICA | Q29983 | 1/20 | 0.39 |
| ▸ | RAET1L | Q5VY80 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14547522 | 1.00 | PPARG (0.61) | PPARGSLC22A12LMNAPOLBHPGD | |
| SCHEMBL13324899 | 1.00 | PPARG (0.61) | PPARGSLC22A12LMNAPOLBHPGD | |
| SCHEMBL12189840 | 0.91 | PPARG (0.60) | PPARGSLC22A12LMNAPOLBHPGD | |
| SCHEMBL3299728 | 0.91 | PPARG (0.60) | PPARGSLC22A12LMNAPOLBHPGD | |
| SCHEMBL3299127 | 0.91 | PPARG (0.60) | PPARGSLC22A12LMNAPOLBHPGD | |
| SCHEMBL3299123 | 0.91 | PPARG (0.60) | PPARGSLC22A12LMNAPOLBHPGD | |
| SCHEMBL13324898 | 0.87 | PPARG (0.62) | PPARGSLC22A12LMNAMAPTHTT | |
| SCHEMBL13359395 | 0.87 | PPARG (0.62) | PPARGSLC22A12LMNAMAPTHTT | |
| SCHEMBL16502054 | 0.83 | PPARG (0.57) | PPARGSLC22A12LMNAMAPTHTT | |
| SCHEMBL13359396 | 0.83 | PPARG (0.57) | PPARGSLC22A12LMNAHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7714131-B2 | Process for the stereoselective preparation of (−)-halofenate and derivatives thereof | METABOLEX, INC. (US) | 2010-05-11 | — | — | US | disclosed |