Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 14/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 11/20 | 0.43 |
| ▸ | DPP9 | Q86TI2 | 11/20 | 0.43 |
| ▸ | FAP | Q12884 | 2/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22375785 | 0.86 | DPP4 (0.45) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL12709888 | 0.82 | DPP4 (0.44) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL19710591 | 0.81 | PIK3CD (0.59) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL12732676 | 0.81 | DPP4 (0.43) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL29415064 | 0.79 | ATM (0.56) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL19334826 | 0.78 | DPP4 (0.70) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL19577902 | 0.78 | ATM (0.39) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL1504386 | 0.76 | DPP4 (0.53) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL16518661 | 0.75 | ATM (0.53) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL2933741 | 0.75 | ATM (0.44) | DPP4DPP8DPP9FAPDPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017192820-A1 | GLP-1 RECEPTOR LIGAND MOIETY CONJUGATED OLIGONUCLEOTIDES AND USES THEREOF | IONIS PHARMACEUTICALS, INC. (US) | 2017-11-09 | — | — | WO | disclosed |
| US-7713944-B2 | Oligomers comprising activated disulfides which bind to plasma proteins and their use for delivery to cells | ISIS PHARMACEUTICALS, INC. (US) | 2010-05-11 | — | — | US | disclosed |