SCHEMBL1336037

SCHEMBL1336037

O=S(=O)(c1cccs1)c1cccs1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LOX P28300 1/20 0.60
PKM P14618 3/20 0.56
CYP2C9 P11712 2/20 0.56
CYP2C19 P33261 2/20 0.56
CYP2D6 P10635 1/20 0.56
F2 P00734 1/20 0.52
PRSS1 P07477 1/20 0.52
PRSS2 P07478 1/20 0.52
PRSS3 P35030 1/20 0.52
ALDH1A1 P00352 4/20 0.50
MAPT P10636 2/20 0.50
LMNA P02545 1/20 0.50
MAPK1 P28482 1/20 0.50
RAB9A P51151 1/20 0.50
CACNA1B Q00975 1/20 0.50
APBA1 Q02410 1/20 0.50
PAX8 Q06710 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50
POLB P06746 2/20 0.48
CYP3A4 P08684 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28533417 0.97 LOX (0.58) LOXPKMCYP2C9CYP2C19CYP2D6
SCHEMBL29186495 0.87 PKM (0.50) LOXPKMCYP2C9CYP2C19CYP2D6
SCHEMBL2933307 0.85 HTR6 (0.56) LOXPKMCYP2C9CYP2C19CYP2D6
SCHEMBL12360244 0.82 LOX (0.46) LOXPKMCYP2C9CYP2C19CYP2D6
SCHEMBL29287801 0.82 HTR6 (0.58) LOXPKMCYP2C9CYP2C19CYP2D6
SCHEMBL329263 0.81
SCHEMBL28965990 0.80 PKM (0.53) LOXPKMCYP2C9CYP2C19CYP2D6
SCHEMBL3041710 0.80 HTR6 (0.50) LOXPKMCYP2C9CYP2C19CYP2D6
SCHEMBL195296 0.79
SCHEMBL2203212 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119912354-A Process for preparing (Z) -N- (1, 4-dioxo-1, 4-diphenylbut-2-en-2-yl) benzamide derivatives 江西科技师范大学 2025-05-02 CN claimed
CN-119912354-A Process for preparing (Z) -N- (1, 4-dioxo-1, 4-diphenylbut-2-en-2-yl) benzamide derivatives 江西科技师范大学 2025-05-02 CN disclosed
CN-117425470-A Antiperspirant compositions 科蒂公司 2024-01-19 CN disclosed
CN-116940326-A Antiperspirant compositions 科蒂公司 2023-10-24 CN disclosed
CN-116367811-A Antiperspirant compositions 科蒂公司 2023-06-30 CN disclosed
CN-114727977-A Process for the preparation of compounds and modulators of compound S1P1 特维娜有限公司 2022-07-08 CN disclosed
CN-112841206-B Methods of controlling ALS-tolerant plant growth 江苏龙灯化学有限公司 2022-05-17 CN disclosed
CN-114158553-A Novel pesticide preparation and preparation method thereof 南开沧州渤海新区绿色化工研究有限公司 2022-03-11 CN disclosed
CN-108601359-B Methods of controlling ALS-tolerant plant growth 江苏龙灯化学有限公司 2021-08-10 CN disclosed
CN-112841206-A Methods of controlling ALS-tolerant plant growth 江苏龙灯化学有限公司 2021-05-28 CN disclosed
US-4565826-A HYPOTENSIVE, CARDIONASCULAR, ANTIULCER, ANTISECRETORY, GASTROINTESTINAL DISORDERS WILLIAM H. RORER, INC. (US) 1986-01-21 US disclosed
EP-0086775-A4 HETEROCYCLIC AMIDINO SUBSTITUTED UREAS AND THEIR PHARMACEUTICAL USES. RORER INTERNAT OVERSEAS INC (US) 1984-09-05 EP disclosed
EP-0078839-A4 HETEROCYCLIC AMIDINOUREAS. RORER INTERNAT OVERSEAS INC (US) 1984-07-25 EP disclosed
US-4436911-A HYPOTENSIVE, ANTISPASMODIC, ANTIULCER, ANTIPARASITIC WILLIAM H. RORER, INC. (US) 1984-03-13 US disclosed
EP-0086775-A1 HETEROCYCLIC AMIDINO SUBSTITUTED UREAS AND THEIR PHARMACEUTICAL USES RORER INTERNATIONAL (OVERSEAS) INC. (US) 1983-08-31 EP disclosed
EP-0079377-A1 HETEROCYCLIC ALKYLENE AMIDINOUREAS RORER INTERNATIONAL (OVERSEAS) INC. (US) 1983-05-25 EP disclosed
EP-0078839-A1 HETEROCYCLIC AMIDINOUREAS RORER INTERNATIONAL (OVERSEAS) INC. (US) 1983-05-18 EP disclosed
WO-1983000627-A1 HETEROCYCLIC AMIDINO SUBSTITUTED UREAS AND THEIR PHARMACEUTICAL USES STUDT, WILLIAM, LYON 1983-03-03 WO disclosed
WO-1982004048-A1 HETEROCYCLIC ALKYLENE AMIDINOUREAS RORER INT OVERSEAS (US) 1982-11-25 WO disclosed
WO-1982004047-A1 HETEROCYCLIC AMIDINOUREAS RORER INT OVERSEAS (US) 1982-11-25 WO disclosed